Results 61 to 70 of about 919,747 (358)

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

Microbiology and Drug Susceptibility Pattern of Bacterial Isolates from Patients with Chronic Suppurative Otitis Media at a Tertiary Care Hospital in Somalia

Infection and Drug Resistance, 2022
Ismail Mohamed Ali,1 Cihan Duman,1 İlkay Bozdağ,2 Abdihakim Artan Abdi,1 Mohamed Nor Abdi,1 Süleyman Emre Karakurt,1 Özgür Yiğit3 1Department of Otorhinolaryngology, Head and Neck Surgery, University of Health Sciences, Somalia Turkey ...
Mohamed Ali I, Duman C, Bozdağ İ, Artan Abdi A, Nor Abdi M, Karakurt SE, Yiğit Ö   +6 more
doaj  

Clinical metagenomics. [PDF]

, 2019
Clinical metagenomic next-generation sequencing (mNGS), the comprehensive analysis of microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly moving from research to clinical laboratories. This emerging approach is changing
Chiu, Charles Y, Miller, Steven A
core  

Influence of molecular structure on the antimicrobial function of phenylenevinylene conjugated oligoelectrolytes. [PDF]

, 2016
Conjugated oligoelectrolytes (COEs) with phenylenevinylene (PV) repeat units are known to spontaneously intercalate into cell membranes. Twelve COEs, including seven structures reported here for the first time, were investigated for the relationship ...
Bazan, Guillermo C, Hinks, Jamie, Rehermann, Carolin, Rengert, Zachary D, Thomas, Alexander W, Yan, Hengjing   +5 more
core   +2 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Antimicrobial resistance to cefotaxime and ertapenem in Enterobacteriaceae: the effects of altering clinical breakpoints

Journal of Infection in Developing Countries, 2014
Introduction: The Clinical and Laboratory Standards Institute (CLSI) updated its antimicrobial susceptibility testing interpretation criteria for Enterobacteriaceae.
Po-Yu Liu, Zhi-Yuan Shi, Kwong-Chung Tung, Ching-Lin Shyu, Kun-Wei Chan, Jai-Wen Liu, Zong-Yen Wu, Chih-Chuan Kao, Yi-Ching Huang, Chin-Fu Lin   +9 more
doaj   +1 more source

Changes in tolerance to herbicide toxicity throughout development stages of phototrophic biofilms [PDF]

, 2013
Ecotoxicological experiments have been performed in laboratory-scale microcosms to investigate thesensitivity of phototrophic biofilm communities to the alachlor herbicide, in relation to the stages ofphototrophic biofilm maturation (age of the ...
Delmas, François, Duran, Robert, Lauga, Béatrice, Paul, Etienne, Paule, Armelle, Rols, Jean-Luc, Roubeix, Vincent   +6 more
core   +4 more sources

Diagnostic Value of Microbial Cell-free DNA Sequencing for Suspected Invasive Fungal Infections: A Retrospective Multicenter Cohort Study

Open Forum Infectious Diseases
Background An early diagnosis and treatment of invasive fungal disease (IFD) is associated with improved outcome, but the moderate sensitivity of noninvasive diagnostic tests makes this challenging.
Sammy Huygens, A. Schauwvlieghe, Nick Wlazlo, I. Moors, J. Boelens, M. Reynders, Ga-Lai M Chong, C. Klaassen, Bart J. A. Rijnders   +8 more
semanticscholar   +1 more source

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source

Antimicrobial activity of different filling pastes for deciduous tooth treatment

Brazilian Oral Research, 2015
Guedes-Pinto paste is the filling material most employed in Brazil for endodontic treatment of deciduous teeth; however, the Rifocort® ointment has been removed. Thus, the aim of this study was to investigate the antimicrobial potential of filling pastes,
Bruna Feltrin ANTONIAZZI, Carine Weber PIRES, Carmela Rampazzo BRESOLIN, Rita Niederauer WEISS, Juliana Rodrigues PRAETZEL   +4 more
doaj   +1 more source