Results 201 to 210 of about 203,892 (307)

Innovative methodology for flexible monitoring of various bioprocesses by using pre‐existing Raman data coupled with automated transfer learning technique

Biotechnology Progress, EarlyView.
The application of the transfer learning algorithm successfully allowed the use of a model built on process A for real‐time monitoring of process B. This study shows the improvement obtained with this methodology compared to the direct application of the model.
Adèle Schini, Hadi El Radi, Johan Cailletaud, Célia Sanchez, Nathan Gay, Bruno Ebel, Emmanuel Guedon, Laurent Jourdainne   +7 more
wiley   +1 more source

Metagenomics profiling of the lower respiratory tract microbiome and relevant respiratory pathogens in pediatric intensive care unit patients: a pilot exploratory study in Egypt. [PDF]

Acute Crit Care
Soliman MS, Abbas AM, Algebaly HF, El-Kholy AA, Soliman NS.   +4 more
europepmc   +1 more source

Scalable desolvation synthesis, storage stability, and comprehensive biophysical characterization of human hemoglobin nanoparticles as a potential hemoglobin‐based oxygen carrier

Biotechnology Progress, EarlyView.
This work describes the development of human hemoglobin nanoparticles using an anti‐solvent precipitation synthesis method as a potential next generation hemoglobin‐based oxygen carrier. The hemoglobin nanoparticles are uniform in size and shape, hemocompatible, stable at various storage conditions, and demonstrate a scalable synthesis technique ...
Alisyn Greenfield, Andre F. Palmer
wiley   +1 more source

Best microbiological practice recommendations for the diagnosis of peri-prosthetic joint infections: the CRIOGO bacteriology reference center network. [PDF]

Ann Clin Microbiol Antimicrob
Bémer P, Plouzeau-Jayle C, Lemarié C, Tande D, Gougeon-Jolivet A, Chenouard R, Lamoureux C, Reissier S, Ruffier d'Epenoux L, Chaufour L, Lartigue MF, Corvec S, on behalf the CRIOGO study group.   +12 more
europepmc   +1 more source

Design of experiments‐guided membrane capture facilitates integration of continuous virus inactivation using Phi6 as a surrogate virus in an intensified downstream process

Biotechnology Progress, EarlyView.
Abstract The growing demand for cost‐efficient and flexible biomanufacturing has increased interest in process‐intensified downstream platforms. This study evaluates an intensified monoclonal antibody (mAb) purification sequence, where two unit operations traditionally performed in batch mode—Protein A capture and low pH virus inactivation (VI)—are ...
Mario Grünberg, Lisa Lipski, Gabriel Fisicaro, Thomas Duvignau, Karolina Meyer‐Heinrichs, Diana Carmen Mocsy, Thomas‐Josef Filz, Bastian Quaas, Alexandra Stützer   +8 more
wiley   +1 more source

Protein hydrolysates in cell culture: Toward multi‐omics characterization

Biotechnology Progress, EarlyView.
While protein hydrolysates are widely used in cell culture applications, they remain undefined and variable products. Multi‐omic characterization evaluating composition and function can transition hydrolysates toward semi‐defined media components.
Michelle Combe, Brandon M. Wrage, Angel Varela‐Rohena, Stanislav Sokolenko   +3 more
wiley   +1 more source

Ceftazidime-avibactam for multidrug and pandrug-resistant gram-negative infections in critically Ill children: a single-center pediatric ıntensive care experience. [PDF]

Eur J Pediatr
Havan M, Arga G, Bülbül YE, Özerdem B, Eyduran E, Aslan AD, Penezoğlu N, İnceli HB, Öcal D, Özdemir H, Çiftci E, Kendirli T.   +11 more
europepmc   +1 more source

On‐deck pH measurement with integrated feedback control on a micro‐scale platform for monoclonal antibody low pH viral inactivation

Biotechnology Progress, EarlyView.
Integrating an automated, on‐deck pH measurement method with feedback control enables precise, real‐time pH adjustment during low pH viral inactivation on a micro‐scale platform. Abstract The increasing demand for efficient monoclonal antibody manufacturing has accelerated the adoption of high throughput process development (HTPD) platforms, which ...
Paras Sharma, Nikolas von den Eichen, Sabine Schweisgut, Lars Robbel, Michael Schmitt, Daniel G. Bracewell   +5 more
wiley   +1 more source

Breastfeeding vs. formula feeding on maternal oral health: periodontal and microbiological changes in the postpartum period: an observational longitudinal study. [PDF]

Front Oral Health
Macrì F, Dipalma G, Inchingolo AM, Inchingolo F, Maspero C, Giannini L.   +5 more
europepmc   +1 more source

Intraosseous sarcoidosis imitating peri‐implantitis: A case study

Clinical Advances in Periodontics, EarlyView.
Abstract Background Sarcoidosis is a multisystem granulomatous disorder of unknown cause, typically affecting the lungs and lymph nodes, but it can also involve the eyes, skin, heart, bones, and other organs. The exact cause is unclear, but genetic factors and environmental triggers like infections, chemicals, or dust may play a role.
Magdalena Orlowska, David S. Gottlieb, Kenneth S. Kornman   +2 more
wiley   +1 more source