Results 31 to 40 of about 5,481,908 (287)

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Validation of +tiDx: a point-of-care diagnostic system for Gram-positive bovine mastitis

Frontiers in Veterinary Science
IntroductionRapid and accurate detection and identification of bovine mastitis-causing pathogens are crucial for treatment decisions and dairy farm management.
Valentina Restrepo-Cano, Arley Caraballo-Guzmán, Miryan Margot Sánchez-Jiménez, Giovanny Torres-Lindarte   +3 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Microbiological and Clinical Findings of SARS-CoV-2 Infection after 2 Years of Pandemic: From Lung to Gut Microbiota

Diagnostics, 2022
Early recognition and prompt management are crucial for improving survival in COVID-19 patients, and after 2 years of the pandemic, many efforts have been made to obtain an early diagnosis.
Alessandro Russo, Francesca Serapide, Angela Quirino, Maria Grazia Tarsitano, Nadia Marascio, Riccardo Serraino, Salvatore Rotundo, Giovanni Matera, Enrico Maria Trecarichi, Carlo Torti   +9 more
doaj   +1 more source

Diagnostic Performance of the BioFire® Joint Infection Panel in Native Septic Arthritis and Periprosthetic Joint Infection: A Retrospective Diagnostic Accuracy Study

Archives of Basic and Clinical Research
Objective: Rapid identification of causative microorganisms is essential in suspected native septic arthritis and periprosthetic joint infection. This study evaluated the diagnostic performance of the BioFire® Joint Infection Panel and assessed its ...
Mehmet Burak Gökgöz, Volkan Gür, Akın Öztürk, İbrahim Doğan, Nedim Batuhan Toğaluğurlu, Harun Dündar, Barış Gülhan, Sümeyye Akyüz, Furkan Yapıcı   +8 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Physicochemical and microbiological characteristics of fruit-based kombucha [PDF]

, 2023
Kombucha is a fermented drink made out of tea leaves, although recently other alternatives were considered as substitutes, such as fruits. Using different types of fruit could affect the characteristics of fruit-based kombucha.
Cahyadi, A.B., Srianta, I., Zubaidah, E., Tewfik, I.   +3 more
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Stool-specimen testing practices adopted by clinical microbiology laboratories in the Veneto Region, Italy

Microbiologia Medica, 2008
In order to correctly analyze data of laboratory diagnoses of infectious gastroenteritis for epidemiological purposes, a survey on analytical methods applied by hospital-based clinical microbiology laboratories has been conducted in the Veneto Region ...
Paolo Spolaore, Ugo Fedeli, Ettore De Canale, Giuseppe Bertollo   +3 more
doaj   +1 more source