Results 71 to 80 of about 5,481,908 (287)

Update on Current Microbiological Techniques for Pathogen Identification in Infectious Endophthalmitis. [PDF]

Int J Mol Sci, 2022
Chun LY, Dahmer DJ, Amin SV, Hariprasad SM, Skondra D.   +4 more
europepmc   +1 more source

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

Advanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer, Ian de Ridder, Mahjoobeh Ehsani, Marasim Khan, Justin Kale, Lukas P. Frenzel, David Andrews, Spyridoula Karamanou, Ana J. Garcia‐Saez, Geert Bultynck   +9 more
wiley   +1 more source

The impact of preservation techniques on bee pollen nutritional value, microbiological stability, and antioxidant properties [PDF]

, 2019
After its collection the bee pollen can present moisture contents that can range from 18% to 25%. These moisture contents, combined with the high nutritional value of bee pollen, provide conditions highly favourable to microorganism growth ...
Falcão, Soraia, Martins, Vitor Manuel Ramalheira, Vilas-Boas, Miguel, Lema, Filipe, Mekki, Imen, Rodrigues, Paula, Tomás, Andreia   +6 more
core   +2 more sources

The value of molecular techniques to diagnose Ureaplasma urealyticum and Nocardia farcinica pleuropneumonia in a patient with diffuse large B-cell lymphoma

International Journal of Infectious Diseases, 2017
An unusual case of pleural empyema related to Nocardia farcinica and Ureaplasma urealyticum, occurring after autologous haematopoietic stem cell transplantation in a 30-year-old patient with lymphoma, is reported.
Etienne Canouï, Kim Blanc, Julien Loubinoux, Sandrine Valade, Cécile Hamard, Aurélie Lefebvre, Sandy Amorim, Cécile Bébéar, Veronica Rodriguez-Nava, David Lebeaux, Odile Launay, Marco Alifano, Antoine Rabbat, Solen Kernéis   +13 more
doaj   +1 more source

New Microbiological Techniques for the Diagnosis of Bacterial Infections and Sepsis in ICU Including Point of Care. [PDF]

Curr Infect Dis Rep, 2021
Peri AM, Stewart A, Hume A, Irwin A, Harris PNA.   +4 more
europepmc   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

MODERN ALGORITHMS OF MICROBIOLOGICAL DIAGNOSTICS OF TUBERCULOSIS

Туберкулез и болезни лёгких, 2018
The article presents the comparative analysis of the microbiological diagnostics algorithm, developed and used in Central Tuberculosis Research Institute and the algorithm of laboratory diagnostics and monitoring of treatment of pulmonary tuberculosis ...
Elina V. Sevastyanova, Larisa N. Chernousova   +1 more
doaj   +1 more source

Unveiling the Taxonomic Diversity and Unprecedented Biosynthetic Treasure of the Phylum Myxococcota

Advanced Science, EarlyView.
Natural products remain vital sources of therapeutics, and the phylum Myxococcota constitutes an especially rich reservoir for them. Based on decades of microbiological efforts, we present 154 new Myxococcota genomes and revise taxonomy quadrupling the number of families and genera.
Amay Ajaykumar Agrawal, Ronald Garcia, Guangyi Chen, Chantal D. Bader, Peter Sullivan, Alexander Popoff, Daniel Krug, Maja Hunter, Sebastian Walesch, Emilia Oueis, Christine Frank, Haowen Zhao, Joachim J. Hug, Sebastian Keller, Pascal Hirsch, Azat Tagirdzhanov, Tatiana Malygina, Mary Victory E. Gutierrez, Alexey Gurevich, Judith Boldt, Boyke Bunk, Jörg Overmann, Ulrich Nübel, Andreas Keller, Olga V. Kalinina, Rolf Müller   +25 more
wiley   +1 more source

Rapid Multiplex Antimicrobial Resistance Profiling and Bacterial Identification by LAP‐MALDI Mass Spectrometry Biotyping

Advanced Science, EarlyView.
Liquid atmospheric pressure matrix‐assisted laser desorption/ionization (LAP‐MALDI) mass spectrometry (MS) provides multiplexed biotyping of microbial cultures using a fast and simple workflow. This is demonstrated for clinically relevant bacteria, resulting in accurate antimicrobial resistance (AMR) detection, speciation by MS/MS sequencing and ...
Lily R. Adair, Shabnam Iyer, Ian M. Jones, Rainer Cramer   +3 more
wiley   +1 more source

Recommendations for microbiological sampling in infected hard-to-heal wounds: an Italian association for cutaneous ulcers (AIUC) perspective

Frontiers in Surgery
Chronic and hard-to-heal wounds represent a significant and growing healthcare burden, frequently complicated by infection and impaired healing. Despite the availability of international guidelines, microbiological assessment in clinical practice remains
Sara Carella, Barbara De Angelis, Barbara Nardi, Francesco Branda, Diego Ceci, Caterina Borghetti, Alessandra Mercuri, Marino Cordellini, Cosimo Maglio, Monica Gonnelli, Riccardo Garcea, Giancarlo Ceccarelli   +11 more
doaj   +1 more source