Results 331 to 340 of about 2,195,321 (395)

System genetic analysis of intestinal cancer and periodontitis development as influenced by aging and diabesity using Collaborative Cross mice

open access: yesAnimal Models and Experimental Medicine, EarlyView.
It is increasingly recognized that young, chow‐fed inbred mice poorly model the complexity of human carcinogenesis in multiple respects. In humans, age and adiposity are the major risk factors for the majority of malignancies. Although the development of genetically engineered mouse models (GEMM) of cancer has recapitulated many aspects of human cancer,
Iqbal M. Lone   +4 more
wiley   +1 more source

Heparin‐Binding Protein in Cerebrospinal Fluid as a Biomarker for Bacterial Meningitis: A Study of Diagnostic Accuracy

open access: yesAnnals of Neurology, EarlyView.
Objective We aimed to evaluate the diagnostic accuracy of heparin‐binding protein (HBP) in cerebrospinal fluid for the diagnosis of bacterial meningitis in patients with a suspected central nervous system infection. Methods This prospective multicenter cohort study determined the diagnostic accuracy of HBP in cerebrospinal fluid (CSF) for bacterial ...
Sabine E. Olie   +6 more
wiley   +1 more source

Corrigendum: Editorial: Antiviral monoclonal antibody therapies. [PDF]

open access: yesFront Cell Infect Microbiol
Florez C, Haslwanter D, Jangra RK.
europepmc   +1 more source

Vitamin B12 Levels Association with Functional and Structural Biomarkers of Central Nervous System Injury in Older Adults

open access: yesAnnals of Neurology, EarlyView.
At low levels of B12, specifically when bound to transcobalamin for cellular uptake, evidence of slower conductivity in the brain could point toward impaired myelin. At high levels of B12, specifically when bound to the biologically inert transport protein haptocorrin, biomarkers of neurodegeneration appear in the serum, indicating neuroaxonal injury ...
Alexandra Beaudry‐Richard   +22 more
wiley   +1 more source

Editorial: Mobile DNA element-driven evolution of bacterial pathogens. [PDF]

open access: yesFront Microbiol
Cloeckaert A   +3 more
europepmc   +1 more source

Synthetische Hochdurchsatz‐Mikroarrays von Peptidoglykan Fragmenten als neuartiges serodiagnostisches Instrument zur Erstellung von Antikörperprofilen bei Patienten

open access: yesAngewandte Chemie, EarlyView.
Mikroarrays von Peptidoglykan‐Fragmenten, die 864 Varianten von Gram‐positiven und Gram‐negativen Bakterien umfassen, wurden mit Hilfe einer neuen On‐Chip‐Synthesetechnologie hergestellt. Diese wurden verwendet, um die Spezifität von monoklonalen Antikörpern zu charakterisieren und Proben von Patienten mit der Autoimmunerkrankung Epidermolysis bullosa ...
Alexandra Tsouka   +12 more
wiley   +1 more source

Author Correction: β-Glucan reprograms neutrophils to promote disease tolerance against influenza A virus. [PDF]

open access: yesNat Immunol
Khan N   +18 more
europepmc   +1 more source

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