Results 71 to 80 of about 931,651 (296)

Advances in fungal vaccine development: Progress in the face of emerging challenges

iScience
Summary: Historically overshadowed by bacterial and viral infections, fungal diseases are resurging globally, fueled by rising antifungal resistance and the increasing vulnerability of immunocompromised populations in healthcare settings.
Munika Moses, Xinhua Huang, Xinying Xue, Changbin Chen   +3 more
doaj   +1 more source

Emerging applications of fluorescence spectroscopy in medical microbiology field [PDF]

, 2009
There are many diagnostic techniques and methods available for diagnosis of medically important microorganisms like bacteria, viruses, fungi and parasites. But, almost all these techniques and methods have some limitations or inconvenience. Most of these
Aamir Shahzad, Gottfried Köhler, Martin Knapp, Erwin Gaubitzer, Martin Puchinger, Michael Edetsberger, Alexandra, Alexandra, N Ramanujam, CG Pack, J Klinger, JR Lakowicz, H Bhatta, Ludovic Leblanc, Ani Sarkissian, Matthew J Sorrell, HE Giana, Tourkya, JW Rippon, Diego Rativa, Köhler   +20 more
core   +1 more source

Enhanced Human Antigen‐Specific B Cell Responses Using In Vitro 3D Tonsil Cultures Containing Stromal Cells

Advanced Healthcare Materials, EarlyView.
We developed a fully human 3D tonsil cell culture system incorporating supportive stromal cells that better sustains and activates immune cells than conventional methods. The model generates stronger, more targeted antibody responses to viral antigens and vaccines, providing a physiologically relevant and entirely human platform for studying immune ...
Maaike V. J. Braham, Marlon de Gast, Liubov Babii, Sabine Kruijer, Theo M. Bestebroer, Mathilde Richard, Mathieu Claireaux, S. Marieke van Ham, Jelle de Wit, Cécile A. C. M. van Els, Anja ten Brinke, Marit J. van Gils   +11 more
wiley   +1 more source

Liver abscess induced by intestinal hypervirulent Klebsiella pneumoniae through down-regulation of tryptophan-IPA-IL22 axis

iScience
Summary: Hypervirulent Klebsiella pneumoniae (hvKp) is a significant causative agent of invasive hepatic abscess syndrome in Asia, presenting substantial clinical challenges due to its intricate pathogenesis.
Xiu You, Liping Wang, Hong Wang, Yizheng Xu, Yongzheng Chen, Huizhen Xu, Xuelian Ji, Xiangsong Ma, Xiuyu Xu   +8 more
doaj   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Emerging bacterial factors for understanding pathogenesis of endometriosis

iScience
Summary: The pathogenesis of endometriosis is a complex process, and recent research has introduced novel hypotheses in this field. This review summarizes recent studies on the pathogenesis of endometriosis. We focused on several classical hypotheses, as
Ayako Muraoka, Akira Yokoi, Hiroaki Kajiyama   +2 more
doaj   +1 more source

Multistrain models predict sequential multidrug treatment strategies to result in less antimicrobial resistance than combination treatment [PDF]

, 2016
Background Combination treatment is increasingly used to fight infections caused by bacteria resistant to two or more antimicrobials. While multiple studies have evaluated treatment strategies to minimize the emergence of resistant strains for single ...
Ahmad, Amais, Christiansen, Lasse Engbo, Græsbøll, Kaare, Matthews, Louise, Nielsen, Søren Saxmose, Olsen, John Elmerdahl, Toft, Nils, Zachariasen, Camilla   +7 more
core   +4 more sources

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Comparison of E-learning and the Classroom Lecture in Microbiology Course Based on Gagne's Instructional Model [PDF]

Research and Development in Medical Education, 2016
Background: This study aims to design and produce electronic content of a microbiology course for students in AJA (Islamic Republic of Iran Army) University of Medical Sciences based on Gagne's instructional design model and determine its effectiveness ...
Mojgan Mohammadimehr, Sanaz Zargar Balaye Jam, Rahim Moradi   +2 more
doaj   +1 more source

Clinical microbiology study of diabetic foot ulcer in Iran; pathogens and antibacterial susceptibility [PDF]

, 2012
The aim of this study was to investigate microbial pathogens and their antibiotic susceptibility profile in infected diabetic foot ulcers in Iranian patients.
Hayatshahi, A., Heshmat, R., Nikoo, M.K., Qorbani, M., Rouhipour, N., Yazdi, N.M.   +5 more
core   +1 more source