Results 61 to 70 of about 29,238 (342)
Advanced ScienceMicrobubble‐enabled focused ultrasound (MB‐FUS) has revolutionized nano and molecular drug delivery capabilities. Yet, the absence of longitudinal, systematic, quantitative studies of microbubble shell pharmacokinetics hinders progress within the MB‐FUS ...
Maneesha A. Rajora +9 more
doaj +1 more source
Cyborg and Bionic SystemsWe previously developed a novel needle-free reagent injection method based on electrically induced microbubbles. The system generates microbubbles and applies repetitive mechanical oscillation associated with microbubble dynamics to perforate tissue and ...
Yibo Ma +3 more
doaj +1 more source
Microbubble intensification of bioprocessing
, 2023 Microbubbles are famed for their large surface area to volume ratio, with the promise of intensification of interfacial phenomena, highlighted by more rapid gas exchange. However, for bioprocessing, it has been recognized for many decades that surfactant-
Desai, P.D. +3 more
core +1 more source
Advanced Science, EarlyView.We developed a RhPd‐H nanozyme that integrates enhanced POD‐mimetic catalytic activity with thermally triggered H2 release. H2 shields and reprograms mitochondria to continuously leak endogenous ·O2−. This dual‐path ROS spatially and temporally disrupts redox homeostasis, inducing persistent oxidative stress for tumor suppression and antitumor immunity,
Mingfan Shi +12 more
wiley +1 more source
Frontiers in Oncology, 2022 Ultrasound targeted microbubble destruction (UTMD) was introduced as a promising method to improve anti-tumor therapeutic efficacy, while minimizing side effects to healthy tissues.
Gonglin Fan +8 more
doaj +1 more source
Advanced Science, EarlyView.We report the development of biotinylated PEGylated bilirubin‐coated perfluoropentane (bt‐PEG‐BR@PFP) nanobubbles, a novel class of ROS‐activatable and dual‐modality contrast agents that amplify both ultrasound (US) and magnetic resonance imaging (MRI) signals in response to elevated ROS.
Wonsik Jung +6 more
wiley +1 more source
Sonothrombolysis with Magnetically Targeted Microbubbles [PDF]
Ultrasound in Medicine & Biology, 2019 Microbubble-enhanced sonothrombolysis is a promising approach to increasing the tolerability and efficacy of current pharmacological treatments for ischemic stroke. Maintaining therapeutic concentrations of microbubbles and drugs at the clot site, however, poses a challenge.
Marie de Saint Victor +5 more
openaire +5 more sources
, 1983 The laser microbubble detector that measures the size and number of microbubbles in extracorporeal blood flow circuit of medical surgery is reported. The microbubbles are mixed into the human blood circuit by using oxygenators during operations.
Murata, Shuichi +25 more
core +1 more source
Noninvasive Focal Gene Delivery into the Cerebellum of Non‐Human Primates using Focused Ultrasound
Advanced Science, EarlyView.Focal and non‐invasive viral vector delivery in non‐human primates remains a major challenge in translational neuroscience. Low‐intensity focused ultrasound was used to transiently open the blood–brain barrier and enable targeted gene delivery to the cerebellum.
Noelia Esteban‐García +11 more
wiley +1 more source
Angewandte Chemie, EarlyView.The strategy of engineering nanogel network topology is developed to achieve iterative activation of mechanophores upon high‐frequency and low‐intensity ultrasound. This places the nanogel system among the systems that can respond to the ultrasound with the highest frequency and lowest intensity as well as have the fastest activation rate so far.
Helin Li +7 more
wiley +2 more sources