Hybrid lipidic and fluorinated polymer microbubbles for blood-brain barrier opening: a comparative study with SonoVue [PDF]
Ultrasonics SonochemistryMicrobubble-mediated focused ultrasound is a promising strategy for transient and localized blood-brain barrier (BBB) permeabilization, enabling drug delivery to the brain.
Ambre Dauba +14 more
doaj +2 more sources
Laser-Controlled Propulsion of a Microbubble Rolling on a Carbon Nanocoil Rail [PDF]
NanomaterialsControllably propelling microbubbles in microchannels within a microfluidic chip is of great scientific significance yet remains challenging. In this work, we employ carbon nanocoils (CNCs) as a laser-energized rail for propelling microbubbles to the ...
Yuli Liu +7 more
doaj +2 more sources
The role of ultrasound-driven microbubble dynamics in drug delivery : from microbubble fundamentals to clinical translation [PDF]
, 2019 In the last couple of decades, ultrasound-driven microbubbles have proven excellent candidates for local drug delivery applications. Besides being useful drug carriers, microbubbles have demonstrated the ability to enhance cell and tissue permeability ...
De Smedt, Stefaan +6 more
core +31 more sources
Preparation of Nanoparticle-Loaded Microbubbles via an Electrohydrodynamic Atomization Process
Applied Sciences, 2022 Microbubbles have been widely used in many research fields due to their outstanding physicochemical properties and unique structural characteristics, especially as ultrasonic contrast agents and drug delivery carriers.
Xin-Bin Nie +5 more
doaj +1 more source
The Impact of Lipid Handling and Phase Distribution on the Acoustic Behavior of Microbubbles
Pharmaceutics, 2021 Phospholipid-coated microbubbles are ultrasound contrast agents that can be employed for ultrasound molecular imaging and drug delivery. For safe and effective implementation, microbubbles must respond uniformly and predictably to ultrasound.
Simone A.G. Langeveld +5 more
doaj +1 more source
On the theory of multiple encapsulated microbubbles interaction: Effect of lipid shell thickness
Case Studies in Thermal Engineering, 2023 Encapsulated microbubbles are empty, micrometer-sized, spherical bubbles, typically micron which are used in many applications as lipid-shells in soft tissues.
Ahmed K. Abu-Nab, Ali F. Abu-Bakr
doaj +1 more source
Micromachines, 2022 Microbubbles have important applications in optofluidics. The generation and growth of microbubbles is a complicated process in microfluidic channels.
Jia-Wen He +5 more
doaj +1 more source
High-speed optical observations of asymmetric pulsations of microbubbles released from tablet matrix
Current Directions in Biomedical Engineering, 2023 Microbubbles with a negligible shell are of utmost importance in the study of harmonic ultrasound contrast agents. The purpose of this study was to collect and quantify experimental pulsation footage of gas microbubbles released from tablet matrix under ...
Anderton Nicole +7 more
doaj +1 more source
Ultrasound assisted siRNA delivery using PEG-siPlex loaded microbubbles [PDF]
, 2008 Short interfering RNA (siRNA) attracts much attention for the treatment of various diseases. However, its delivery, especially via systemic routes, remains a challenge. Indeed, naked siRNAs are rapidly degraded, while complexed siRNAs massively aggregate
De Smedt, Stefaan +4 more
core +1 more source
Ultrasound localization microscopy to image and assess microvasculature in a rat kidney. [PDF]
, 2017 The recent development of ultrasound localization microscopy, where individual microbubbles (contrast agents) are detected and tracked within the vasculature, provides new opportunities for imaging the vasculature of entire organs with a spatial ...
Ferrara, Katherine W +5 more
core +3 more sources