Results 221 to 230 of about 26,334 (268)

Therapeutic applications of microbubbles

European Journal of Radiology, 2002
Microbubbles, currently used as contrast agents have potential therapeutic applications. Microbubbles, upon insonation of sufficiently intense ultrasound will cavitate. Cavitation with microbubbles can be used to dissolve blood clots or deliver drugs. Targeting ligands and drugs can be incorporated into microbubbles to make highly specific diagnostic ...
Evan C Unger
exaly   +3 more sources

The Onset of Microbubble Vibration

Ultrasound in Medicine & Biology, 2007
A linear relationship between the relative expansion of an off-resonance ultrasound contrast microbubble and low acoustic pressures is expected. In this study, high-speed optical recordings of individual phospholipid-coated microbubbles were used to investigate this relationship for microbubbles ranging from 2 to 11 microm and for acoustic pressures ...
Emmer, M., van Wamel, Annemieke, Goertz, David E., de Jong, N.   +3 more
openaire   +3 more sources

Microbubble intensification of bioprocessing

2020
Microbubbles have been involved in industrial processing since the 1970s with the introduction of dissolved air flotation into common practice. The turn of the century saw microbubbles become regularly used in medical imaging. But in bioprocessing, only this decade has seen rapid advances in R&D, with some bioprocesses, particularly in wastewater ...
D J, Gilmour, W B, Zimmerman
openaire   +2 more sources

Interaction of Microbubbles with Ultrasound

Echocardiography, 1999
The clinical need for bedside myocardial perfusion studies is obvious in the present era of revascularization. Animal and first clinical studies suggest that microbubbles can be used as intravascular tracers of perfusion in conjunction with echocardiography as an imaging modality.
Helene, Von Bibra, Jens-Uwe, Voigt, Mats, Fröman, Dianna, Bone, Bengt, Wranne, Anders, Juhlin-Dannfeldt   +5 more
openaire   +2 more sources

Ultrasound, microbubbles, and thrombolysis

Progress in Cardiovascular Diseases, 2001
Although dissolution of thrombus using ultrasound has been attempted for over 25 years, the clinical use of this technique remains limited. The ability of microbubbles to potentiate ultrasound-induced thrombolysis has renewed interest in this technique, which recanalizes occluded vessels without the need for fibrinolytic therapy.
T R, Porter, F, Xie
openaire   +2 more sources

Microbubbles for Medical Applications

2014
Ultrasound contrast agent (UCA) suspensions contain encapsulated microbubbles with radii ranging from 1 to 10 micrometers. The bubbles oscillate to the driving ultrasound pulse generating harmonics of the driving ultrasound frequency. This feature allows for the discrimination of non-linear bubble echoes from linear tissue echoes facilitating the ...
Segers, T.J., de Jong, N., Lohse, Detlef, Versluis, Michel   +3 more
openaire   +2 more sources

The lung as a filter for microbubbles

Journal of Applied Physiology, 1979
A new ultrasonic Doppler device has been used noninvasively over the femoral artery of anesthetized dogs to prove that it can detect carefully calibrated microbubbles of 14--189 micrometers diam when these are infused directly into the aorta. The same evaluated technique has then been employed to detect any bubbles escaping into the arterial system ...
B D, Butler, B A, Hills
openaire   +2 more sources

The microbubble or the microparticle?

Journal of Applied Physiology, 2011
decompression sickness (DCS) has long been attributed to physical forces exerted by inert gas bubbles that may form in tissues, resulting in vascular occlusion and tissue disruption. Bubble formation occurs when a decrease in ambient pressure exceeds the rate at which soluble inert gas (e.g.,
Martha Sue Carraway, Nigel S. Key
openaire   +1 more source

Multifunctional Ultrasound Microbubbles

Chemical Reviews
Microbubbles (MBs) have served as ultrasound (US) contrast agents for over 30 years in cardiac imaging and liver tumor characterization. Moreover, in recent years, molecularly targeted MBs are currently under clinical evaluation for oncological and inflammatory diseases.
Roman A. Barmin, Mirjavad Moosavifar, Andreas Herrmann, Fabian Kiessling, Twan Lammers, Roger M. Pallares   +5 more
openaire   +2 more sources

Enzymatic microbubble robots

Nature Nanotechnology
The development of micro- and nanorobots has amplified the demand for intelligent multifunctional machines in biomedical applications, but most microrobotic systems struggle to achieve the attributes needed for those applications. Here we introduce enzymatic microbubble robots that exhibit steerable motion, enhanced biodegradability, high in vivo ...
Songsong Tang, Hong Han, Xiaotian Ma, Payal N. Patel, Chen Gong, Junhang Zhang, Ernesto Criado-Hidalgo, Jounghyun Yoo, Jiahong Li, Gwangmook Kim, Shukun Yin, Di Wu, Mikhail G. Shapiro, Qifa Zhou, Wei Gao   +14 more
openaire   +2 more sources