Results 11 to 20 of about 42,194 (282)

Microbubbles Stabilized by Protein Shell: From Pioneering Ultrasound Contrast Agents to Advanced Theranostic Systems

open access: yesPharmaceutics, 2022
Ultrasound is a widely-used imaging modality in clinics as a low-cost, non-invasive, non-radiative procedure allowing therapists faster decision-making.
Polina G. Rudakovskaya   +5 more
doaj   +2 more sources

Internalization of targeted microbubbles by endothelial cells and drug delivery by pores and tunnels

open access: yesJournal of Controlled Release, 2022
Ultrasound insonification of microbubbles can locally enhance drug delivery by increasing the cell membrane permeability. To aid development of a safe and effective therapeutic microbubble, more insight into the microbubble-cell interaction is needed. In
Simone Langeveld   +2 more
exaly   +2 more sources

Acoustic trapping of microbubbles in complex environments and controlled payload release

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Significance Remote positioning and activation of drug-loaded microparticles in vivo are a central pursuit of nanomedicine. Optical, magnetic, and acoustic fields have been used to position and sort microparticles in vitro, but the translation in vivo ...
Valeria Garbin   +2 more
exaly   +2 more sources

Sonoporation Using Nanoparticle-Loaded Microbubbles Increases Cellular Uptake of Nanoparticles Compared to Co-Incubation of Nanoparticles and Microbubbles

open access: yesPharmaceutics, 2021
Therapeutic agents can benefit from encapsulation in nanoparticles, due to improved pharmacokinetics and biodistribution, protection from degradation, increased cellular uptake and sustained release.
Yrr Mørch   +2 more
exaly   +3 more sources

Laser-Controlled Propulsion of a Microbubble Rolling on a Carbon Nanocoil Rail [PDF]

open access: yesNanomaterials
Controllably propelling microbubbles in microchannels within a microfluidic chip is of great scientific significance yet remains challenging. In this work, we employ carbon nanocoils (CNCs) as a laser-energized rail for propelling microbubbles to the ...
Yuli Liu   +7 more
doaj   +2 more sources

Preparation of Nanoparticle-Loaded Microbubbles via an Electrohydrodynamic Atomization Process

open access: yesApplied Sciences, 2022
Microbubbles have been widely used in many research fields due to their outstanding physicochemical properties and unique structural characteristics, especially as ultrasonic contrast agents and drug delivery carriers.
Xin-Bin Nie   +5 more
doaj   +1 more source

The Impact of Lipid Handling and Phase Distribution on the Acoustic Behavior of Microbubbles

open access: yesPharmaceutics, 2021
Phospholipid-coated microbubbles are ultrasound contrast agents that can be employed for ultrasound molecular imaging and drug delivery. For safe and effective implementation, microbubbles must respond uniformly and predictably to ultrasound.
Simone A.G. Langeveld   +5 more
doaj   +1 more source

Ultrasound-responsive catalytic microbubbles enhance biofilm elimination and immune activation to treat chronic lung infections

open access: yesScience Advances, 2023
Efficient treatment of chronic lung infections caused by Pseudomonas aeruginosa biofilms is a great challenge because of drug tolerance and immune evasion issues.
Weijun Xiu   +16 more
semanticscholar   +1 more source

Microbubbles for human diagnosis and therapy.

open access: yesBiomaterials, 2023
Microbubbles (MBs) were observed for the first time in vivo as a curious consequence of quick saline injection during ultrasound (US) imaging of the aortic root, more than 50 years ago.
Louise Fournier   +2 more
semanticscholar   +1 more source

Targeted Microbubbles for Drug, Gene, and Cell Delivery in Therapy and Immunotherapy

open access: yesPharmaceutics, 2023
Microbubbles are 1–10 μm diameter gas-filled acoustically-active particles, typically stabilized by a phospholipid monolayer shell. Microbubbles can be engineered through bioconjugation of a ligand, drug and/or cell.
James Kwan   +4 more
semanticscholar   +1 more source

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