Results 81 to 90 of about 29,900 (262)

Longitudinal Awake Mouse Brain Imaging Using Functional Ultrasound and Functional Ultrasound Localization Microscopy

Advanced Science, EarlyView.
Awake longitudinal multimodal ultrasound imaging integrates functional ultrasound (fUS), ultrasound localization microscopy (ULM), and functional ULM (fULM) to characterize cerebrovascular function, microvascular architecture, and flow dynamics within the same animals over time.
Zhe Huang, Yike Wang, Matthew R. Lowerison, Yue Xu, Murong Yi, Bing‐Ze Lin, YiRang Shin, Nathiya Vaithiyalingam Chandra Sekaran, Daniel A. Llano, Pengfei Song   +9 more
wiley   +1 more source

Glutaminolysis Blockade‐Empowered Bimodal Nanodepot for Spatially Complementary Sono‐Thermal Ablation via PANoptosis and STING Activation Against Large Tumors

Advanced Science, EarlyView.
An injectable bimodal TCPD nanodepot disrupts glutaminolysis and TCA metabolism, sensitizing large tumors to spatially complementary sono‐thermal ablation for complete treatment coverage. This intervention induces mitochondrial and endoplasmic reticulum dysfunction, genotoxicity, and NAD+ depletion, converging to trigger PANoptosome assembly and ...
Yi‐Ming Liu, Juan Qin, Si‐Yuan Wu, Xue‐Zhen Zhu, Yun‐Fei Cai, Pei‐Yao Sun, Hao Yang, Xing‐Yue Wang, Shu Li, Duo Wang, Hai‐Dong Zhu   +10 more
wiley   +1 more source

All-Optical Formation and Manipulation of Microbubbles on a Porous Gold Nanofilm

Micromachines, 2020
Microbubble generation and manipulation in aqueous environments are techniques that have attracted considerable attention for their microfluidic and biological applications.
Qin Cao, Tianli Wu, Xixi Chen, Zhiyong Gong, Ahao Wen   +4 more
doaj   +1 more source

Development of Ultrasound Microbubbles and Phase Shift Microbubbles in Theranostics. [PDF]

Wiley Interdiscip Rev Nanomed Nanobiotechnol
ABSTRACT Ultrasound is widely used for diagnostic imaging and therapy. Microbubbles (MB) are effective reflectors of ultrasound and cavitation enhancers, hence their roles in diagnostic and therapeutic ultrasound. MB must be of controlled size, concentration, biocompatible, and stable for biomedical use.
Meuillet EJ, Unger EC.
europepmc   +2 more sources

Low‐Intensity Ultrasound‐Triggered Microbubble Cavitation Attenuates Diabetic Kidney Injury Partially by Reversing Endothelial Dysfunction

Advanced Science, EarlyView.
Non‐invasive low‐intensity pulsed ultrasound ‐triggered cavitation of clinically approved diagnostic‐grade microbubbles delivers favorable mechanical stimuli to renal microvasculature. This intervention restores renal microvascular homeostasis, alleviates DKD‐associated histological and functional damage, and suppresses inflammatory and fibrotic ...
Yubo Lai, Liang Zhang, Wenxin Tao, Jieyuan An, Lantian Wang, Zhaoyou Liu, Guodong Yang, Pengying Wu, Lijun Yuan   +8 more
wiley   +1 more source

Ultrasound and microbubbles-mediated gene transfer ; development of cationic microbubbles

, 2013
Ultrasound and microbubbles-mediated gene transfer is a controlled DNA delivery technique that is less invasive and more effective at targeted delivery than other currently available approaches.
Mesihović, Anida
core   +2 more sources

Photoacoustic radiation force on a microbubble

Physical Review E, 2014
We investigate the radiation force on a microbubble due to the photoacoustic wave which is generated by using a pulsed laser. In particular, we focus on the dependence of pulsed laser parameters on the radiation force. In order to do so, we first obtain a new and comprehensive analytical solution to the photoacoustic wave equation based on the Fourier ...
Erkol, Hakan, Aytac-Kipergil, Esra, Unlu, Mehmet Burcin   +2 more
openaire   +3 more sources

Acoustically Activatable Drug‐Loaded Nanodroplets for Mechanochemical Therapy in Solid Tumors

Advanced Science, EarlyView.
Microfluidically fabricated drug‐loaded nanodroplets are sequentially activated by dual‐frequency ultrasound through acoustic droplet vaporization followed by bubble collapse, enabling spatially controlled drug release and mechanical tumor fractionation, resulting in synergistic mechanochemotherapy and prolonged survival.
Tiran Bercovici, Mike Bismuth, Meir Goldsmith, Dan Peer, Tali Ilovitsh   +4 more
wiley   +1 more source

Experimental investigation on suppression of microbubbles to slug flow in vertical pipeline

, 2019
The microbubbles with the diameter of being less than 50 μm were uneasy to aggregate in fluid, and thus a method was proposed to suppress slug flow by the addition of microbubbles.
Fang, Z, Li, J, Zhaolu, H, Tang, Z, Xu, C   +4 more
core   +1 more source

Microbubble dynamics in brain microvessels.

PLoS ONE
Focused ultrasound stimulation of microbubbles is being tested in clinical trials for its ability to deliver drugs across the blood-brain barrier (BBB). This technique has the potential to treat neurological diseases by preferentially delivering drugs to
James H Bezer, Paul Prentice, William Lim Kee Chang, Sophie V Morse, Kirsten Christensen-Jeffries, Christopher J Rowlands, Andriy S Kozlov, James J Choi   +7 more
doaj   +1 more source