Results 11 to 20 of about 42,123 (276)
Pharmaceutics, 2022 Ultrasound is a widely-used imaging modality in clinics as a low-cost, non-invasive, non-radiative procedure allowing therapists faster decision-making.
Polina G. Rudakovskaya +5 more
doaj +2 more sources
Internalization of targeted microbubbles by endothelial cells and drug delivery by pores and tunnels
Journal of Controlled Release, 2022 Ultrasound insonification of microbubbles can locally enhance drug delivery by increasing the cell membrane permeability. To aid development of a safe and effective therapeutic microbubble, more insight into the microbubble-cell interaction is needed. In
Simone Langeveld +2 more
exaly +2 more sources
Acta Pharmaceutica Sinica B, 2023 Lipid-coated microbubbles are widely used as an ultrasound contrast agent, as well as drug delivery carriers. However, the two main limitations in ultrasound diagnosis and drug delivery using microbubbles are the short half-life in the blood system, and ...
Junsang Doh +2 more
exaly +3 more sources
Laser-Controlled Propulsion of a Microbubble Rolling on a Carbon Nanocoil Rail [PDF]
NanomaterialsControllably propelling microbubbles in microchannels within a microfluidic chip is of great scientific significance yet remains challenging. In this work, we employ carbon nanocoils (CNCs) as a laser-energized rail for propelling microbubbles to the ...
Yuli Liu +7 more
doaj +2 more sources
Preparation of Nanoparticle-Loaded Microbubbles via an Electrohydrodynamic Atomization Process
Applied Sciences, 2022 Microbubbles have been widely used in many research fields due to their outstanding physicochemical properties and unique structural characteristics, especially as ultrasonic contrast agents and drug delivery carriers.
Xin-Bin Nie +5 more
doaj +1 more source
The Impact of Lipid Handling and Phase Distribution on the Acoustic Behavior of Microbubbles
Pharmaceutics, 2021 Phospholipid-coated microbubbles are ultrasound contrast agents that can be employed for ultrasound molecular imaging and drug delivery. For safe and effective implementation, microbubbles must respond uniformly and predictably to ultrasound.
Simone A.G. Langeveld +5 more
doaj +1 more source
Science Advances, 2023 Efficient treatment of chronic lung infections caused by Pseudomonas aeruginosa biofilms is a great challenge because of drug tolerance and immune evasion issues.
Weijun Xiu +16 more
semanticscholar +1 more source
Microbubbles for human diagnosis and therapy.
Biomaterials, 2023 Microbubbles (MBs) were observed for the first time in vivo as a curious consequence of quick saline injection during ultrasound (US) imaging of the aortic root, more than 50 years ago.
Louise Fournier +2 more
semanticscholar +1 more source
Targeted Microbubbles for Drug, Gene, and Cell Delivery in Therapy and Immunotherapy
Pharmaceutics, 2023 Microbubbles are 1–10 μm diameter gas-filled acoustically-active particles, typically stabilized by a phospholipid monolayer shell. Microbubbles can be engineered through bioconjugation of a ligand, drug and/or cell.
James Kwan +4 more
semanticscholar +1 more source
Focused ultrasound/microbubbles-assisted BBB opening enhances LNP-mediated mRNA delivery to brain.
Journal of Controlled Release, 2022 Messenger RNA (mRNA) medicine has become a new therapeutic approach owing to the progress in mRNA delivery technology, especially with lipid nanoparticles (LNP). However, mRNA encapsulated-LNP (mRNA-LNP) cannot spontaneously cross the blood-brain barrier
Koki Ogawa +10 more
semanticscholar +1 more source