Results 251 to 260 of about 88,636 (324)

Early life functional transitions impact craniofacial morphology in osteogenesis imperfecta

The Anatomical Record, Volume 308, Issue 12, Page 3157-3174, December 2025.
Abstract Early life behaviors have a profound role in shaping adult craniofacial morphology. During early life, all mammals undergo the dynamic transition from suckling to mastication, a period coinciding with rapid cranial biomineralization. Osteogenesis imperfecta (OI), a genetic disorder that impacts the production of type I collagen, disrupts ...
Courtney A. Miller, Tanusha Emanuel, Rachel A. Menegaz   +2 more
wiley   +1 more source

Relative and attributable risks of neurological and perinatal adverse outcomes among children with and without prenatal Zika virus exposure in Northeast Brazil: A prospective cohort study (2015-2018). [PDF]

PLoS Negl Trop Dis
Fontes JMSSA, Miranda-Filho DB, Montarroyos UR, de Araújo TVB, Turchi Martelli CM, Rodrigues LC, Brickley E, de Albuquerque MFPM, Souza WV, Ventura LMVO, Ventura CVO, Gois AL, Gouveia MCL, Oliveira DMDS, Eickmann SH, Carvalho MDCG, da Silva PFS, Rocha MÂW, Ramos RCF, Brandão-Filho SP, Cordeiro MT, Bezerra LCA, Dimech GS, Alves SV, Ferreira Neto PP, Castanha PMDS, Dhalia R, Marques ETA, Fulco GRN, Silva MVM, Ximenes RAA, Microcephaly Epidemic Research Group (MERG).   +31 more
europepmc   +1 more source

Zika Virus Infection and Immuno-Cross-Reactivity to Dengue: An Issue in the Pathogenesis of Congenital Microcephaly [PDF]

, 2016
Sora Yasri, Viroj Wiwanikit
openalex   +1 more source

Ultra‐Conserved Poison Exons Enable Rapid and Safe Splicing Factor Gene Expression Switches: A Hypothesis

BioEssays, Volume 47, Issue 12, December 2025.
Here, we suggest that negative autoregulation (NAR) by poison exon splicing enables splicing factors to rapidly and efficiently switch expression in response to transcription changes. This would prevent potentially dangerous levels of splicing factor proteins accumulating in vulnerable cell types and help explain poison exon ultra‐conservation ...
Caroline Dalgliesh, Farimah Ghorbani, Adam J. M. Wollman, David J. Elliott   +3 more
wiley   +1 more source

7p21.1 Microdeletion Encompassing the ACTB Gene in a Japanese Child: Longitudinal Clinical and Neuroimaging Findings. [PDF]

Cureus
Yokoyama K, Mamada M.
europepmc   +1 more source

ATRX: From Chromatin Remodeling to Disease

genesis, Volume 63, Issue 6, December 2025.
ABSTRACT Chromatin remodeling proteins are evolutionarily conserved factors involved in a wide range of biological processes. In this review, we describe ATRX, a chromatin remodeling protein belonging to the SWI/SNF2 family. Its association with different protein complexes, and its roles in embryonic development, sexual differentiation, as well as ...
Mauro Magaña‐Acosta, Viviana Valadez‐Graham   +1 more
wiley   +1 more source

A Further Case Supporting PDCD6IP as the Gene Responsible for a Neurodevelopmental Disorder With Microcephaly. [PDF]

Clin Genet
D'Alessio AM, Torella A, Morleo M, Nigro V, TUDP Study Group, Brunetti-Pierri N.   +5 more
europepmc   +1 more source

Estimation of the expected number of cases of microcephaly in Brazil as a result of Zika

, 2019
Yanfeng Liang, David Greenhalgh
openalex   +1 more source

Lysine Acetyltransferase 6 in Health and Disease

MedComm, Volume 6, Issue 12, December 2025.
KAT6A and its paralog KAT6B have emerged as druggable targets for the treatment of malignancies, especially for breast cancer. Recent progress in drug discovery has promoted the development of dual inhibitors targeting KAT6A and KTA6B, which shows potent antitumor efficacy and manageable toxicity.
Yujing Tan, Jiani Wang, Fei Ma
wiley   +1 more source

Orofacial myofunctional and anthropometric characteristics of children with and without microcephaly: a case-control study. [PDF]

J Appl Oral Sci
Medeiros AMC, Nobre GRD, Rezende GDES, Barreto ÍDC, Cardenas JEV, Nascimento SCS, Matos ALDS, Pereira ASM, Gurgel RQ, Berretin-Felix G.   +9 more
europepmc   +1 more source