Results 251 to 260 of about 58,257 (335)
Electroanalysis, Volume 37, Issue 12, December 2025.An electrochemical biosensor for Zika virus (ZIKV) detection is described. A DNA probe was immobilized on a gold electrode. After hybridization with the target (ZIKV), safranin was used as an intercalating indicator. Detection was performed by differential pulse voltammetry (DPV), where the current signal increases with the target concentration.
Luiz F. G. Luz +3 more
wiley +1 more source
Insights in the underlying pathophysiology of brain malformations associated with VRK1-related syndrome derived from fetal neuropathology. [PDF]
J Neuropathol Exp NeurolTessier A +7 more
europepmc +1 more source
Using brain organoids to understand Zika virus-induced microcephaly
Development, 2017 Xuyu Qian +4 more
semanticscholar +1 more source
Lysine Acetyltransferase 6 in Health and Disease
MedComm, Volume 6, Issue 12, December 2025.KAT6A and its paralog KAT6B have emerged as druggable targets for the treatment of malignancies, especially for breast cancer. Recent progress in drug discovery has promoted the development of dual inhibitors targeting KAT6A and KTA6B, which shows potent antitumor efficacy and manageable toxicity.
Yujing Tan, Jiani Wang, Fei Ma
wiley +1 more source
SHQ1-related hypomyelinating leukodystrophy: A case report with imaging features and a homozygous variant. [PDF]
Radiol Case RepAlBathi A, AlMutairi A, AlDraihem A.
europepmc +1 more source
MedComm, Volume 6, Issue 12, December 2025.Alternative splicing (AS) expands proteomic diversity and functional complexity in eukaryotes, regulated by spliceosomal components, RNA elements, and epigenetic modifications. Dysregulated AS contributes to diseases, including cancer, neurodegenerative disorders, and cardiovascular conditions, among others. Therapeutic interventions, such as antisense
Zhi‐Min Zhu +5 more
wiley +1 more source
A Novel STAG2 Frameshift Variant in Mullegama-Klein-Martinez Syndrome with Complex Conotruncal Heart Defect. [PDF]
Genes (Basel)Wang H.
europepmc +1 more source
P4‐ATPases as Phospholipid Flippases: From Membrane Dynamics to Human Disorders
Medicine Bulletin, Volume 1, Issue 2, Page 121-135, December 2025.ABSTRACT P4‐ATPases (P4 subfamily of P‐type ATPases) flippase complex includes an α‐subunit responsible for catalysis and a supporting β‐subunit, which consumes energy by catalyzing the hydrolysis of ATP, thereby facilitating the translocation of aminophospholipids from the outer to the inner leaflet of cellular membranes to maintain the asymmetric ...
Guangyi Chen, Yeming Yang, Xianjun Zhu
wiley +1 more source
Modeling craniofacial spliceosomopathies: a pathway toward deciphering disease mechanisms. [PDF]
Front Cell Dev BiolGriffin C.
europepmc +1 more source