Programmable Self‐Heating Microneedle Patch for on‐Demand Postprandial Glucose Management
A programmable self‐heating microneedle patch enables on‐demand, timed‐sequence insulin delivery via user‐triggered quadrant activation. Each activation generates localized heat that melts a phase‐change barrier, accelerating drug release. In diabetic rats, sequential quadrant activation counteracts four meal‐mimicking glucose spikes over 24 h without ...
Yang Zhao +9 more
wiley +1 more source
Microfinger robot with inhaling channels for active sampling and analyzing gaseous and liquid substances toward source localization. [PDF]
Konishi S +4 more
europepmc +1 more source
This work presents a large‐cell‐compatible droplet microfluidic platform that overcomes long‐standing barriers in plant cell culture by enabling high‐fidelity encapsulation, novel multilayer 3D droplet incubation for scalable long‐term culture, and support for the full developmental progression of large plant cells.
Arman Mirmiran +10 more
wiley +1 more source
A self-triggering and fully sustainable gastric device enabling long-acting oral delivery of macromolecules. [PDF]
Lu C +20 more
europepmc +1 more source
Acoustically Activatable Drug‐Loaded Nanodroplets for Mechanochemical Therapy in Solid Tumors
Microfluidically fabricated drug‐loaded nanodroplets are sequentially activated by dual‐frequency ultrasound through acoustic droplet vaporization followed by bubble collapse, enabling spatially controlled drug release and mechanical tumor fractionation, resulting in synergistic mechanochemotherapy and prolonged survival.
Tiran Bercovici +4 more
wiley +1 more source
Simulation-guided biomimetic sharp-edged ultrasonic microreactor enables morphology-uniform and performance-tunable halide perovskite quantum dots. [PDF]
Zhu S +8 more
europepmc +1 more source
Flexible tactile sensors have considerable potential for broad application in healthcare monitoring, human–machine interfaces, and bioinspired robotics. This review explores recent progress in device design, performance optimization, and intelligent applications. It highlights how AI algorithms enhance environmental adaptability and perception accuracy
Siyuan Wang +3 more
wiley +1 more source
Optimization the synergy of magnetic whole cell technology and microfluidic reactor for the production of epoxidized fatty acids from vegetable oil refinery by-product. [PDF]
Tohfegar E, Habibi A.
europepmc +1 more source
A Computational Approach for Biomimetic Design of Liver‐On‐A‐Chip
A biomimetic liver‐on‐a‐chip with antiparallel perfusion was designed using COMSOL‐guided simulation to replicate hepatic acinus transport. Full‐scale modelling revealed diffusion‐dominated, length‐dependent nutrient gradients and low‐shear conditions.
Zhenxu Yang +9 more
wiley +1 more source
Gaseous liquid nitrogen-assisted cryo-printing strategies for challenging volumetric anisotropic tissues fabrication. [PDF]
Gao Z +13 more
europepmc +1 more source

