Abstract figure legend Inwardly rectifying (Kir2) and ATP‐sensitive (KATP) potassium channels are functionally expressed in human pulmonary artery endothelial and smooth muscle cells. The schematic illustrates how Kir2‐ and KATP‐mediated K+ efflux contributes to VM regulation and pulmonary vascular tone.
Bianca Barreira +7 more
wiley +1 more source
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley +1 more source
Artesunate preserves post-resuscitation myocardial and neurologic function in a rat model of cardiac arrest and cardiopulmonary resuscitation. [PDF]
Li H +8 more
europepmc +1 more source
Abstract figure legend Benefits of performing physical exercise at moderate altitude. At moderate altitude, increased resting metabolic rate and physical exertion promote physical fitness and exercise tolerance, whereas hypoxia suppresses appetite and elicits adaptations that increase tissue O2 delivery while augmenting O2‐independent ATP production ...
Robert T. Mallet +6 more
wiley +1 more source
Role of Final Kissing Balloon Inflation in Left Main Distal Bifurcation Single Stenting: Insights from Angiographic Microvascular Resistance. [PDF]
Chen E, Hu D, Zheng H, Chen L, Cai W.
europepmc +1 more source
Automated 3D reconstruction of the normal and cirrhotic rat hepatic microcirculation using confocal microscopy: a feasibility study [PDF]
De Vos, Winnok +6 more
core +1 more source
Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies.
Silvia Marchianò +18 more
wiley +1 more source
OCT Angiography-Based Quantitative Choroidal Vasculature Analysis in Choroidal Melanomas and Nevi. [PDF]
Kurdiani T +3 more
europepmc +1 more source
Vasopressor Use in Acute Burn Resuscitation: A Retrospective Study
ABSTRACT Background Vasopressors are often introduced in severe burn patients who respond poorly to fluid resuscitation to maintain adequate blood pressure and avoid fluid creep. This study aims to characterise these patients and explore potential correlations between vasopressor use and patient outcomes.
Kristine Knappskog +9 more
wiley +1 more source
Coupled Plasma Filtration and Adsorption in Eliminating Inflammatory Mediators and Enhancing Sublingual Microcirculation in Severe Acute Pancreatitis. [PDF]
Zhou H, Ma C, Zhong S.
europepmc +1 more source

