Results 91 to 100 of about 52,627 (301)

A Hypothalamic Oxytocinergic–Sympathetic Axis Couples Anxiety Dysregulation With Impaired Tendon–Bone Repair

open access: yesAdvanced Science, EarlyView.
RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan   +8 more
wiley   +1 more source

Investigation of the role of afterhyperpolarizaÜon potential in the formation of the electrical signals in some brain cells of mouse, rat and helix aspersa [PDF]

open access: yesEurasian Journal of Veterinary Sciences
In this study, using the double and sharp microelectrodes and patch clamp techniques, intracellular recordings were performed in the neurons of mice cochlear nucleus, rat inferior colliculus and subesophagial ganglia ol Helix aspersa in vitro.
Ramazan Bal
doaj  

A Chiral Virus‐Like Nanoplatform That Broadly Mediates Antibiotic Delivery to the Brain for Bacterial Meningitis Therapy

open access: yesAdvanced Science, EarlyView.
Chiral virus‐mimicking mesoporous silica nanostructures (CVSNs) efficiently transport diverse antibiotics across the blood–brain barrier (BBB) into brain parenchyma and cerebrospinal fluid. By enhancing delivery to microglia and astrocytes, CVSNs improve antibiotic bioavailability and therapeutic efficacy against both Gram‐negative and Gram‐positive ...
Qianqian Xu   +11 more
wiley   +1 more source

Modelling of Impulsional pH Variations Using ChemFET-Based Microdevices: Application to Hydrogen Peroxide Detection

open access: yesSensors, 2014
This work presents the modelling of impulsional pH variations in microvolume related to water-based electrolysis and hydrogen peroxide electrochemical oxidation using an Electrochemical Field Effect Transistor (ElecFET) microdevice.
Abdou Karim Diallo   +3 more
doaj   +1 more source

A Water Compartment Cell Culture Lid Enables Stable Longitudinal Recording of Neuronal Networks In Vitro

open access: yesAdvanced Science, EarlyView.
A cell culture lid with an integrated water compartment eliminates evaporation from microelectrode arrays while preserving gas exchange. Freed from the osmotic drift and repeated medium exchanges that disturb conventional recordings, patterned human iPSC‐derived neuronal networks are recorded continuously for five weeks. Single‐spike resolution reveals
Benedikt Maurer   +4 more
wiley   +1 more source

Surface enhanced Raman spectroscopic monitor of P. acnes lipid hydrolysis in vitro

open access: yesJournal of Lipid Research, 1998
Surface enhanced Raman spectroscopy (SERS) at a silver microelectrode was used to monitor bacterial hydrolysis of triglycerides in lipid mixtures that model sebaceous gland secretions.
Millicent K. Weldon   +3 more
doaj   +1 more source

Lactate Homeostasis Disruption Potentiates TACE‐Immunotherapy in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Lactate homeostasis is disrupted through spatially coordinated extracellular neutralization and intracellular acidification, triggering calcium overload, mitochondrial dysfunction, and immunogenic cell death. This metabolic reprogramming alleviates the immunosuppressive tumor microenvironment and enhances immune checkpoint blockade, providing a ...
Minjiang Chen   +12 more
wiley   +1 more source

Motor Evoked Potentials Improve Targeting in Deep Brain Stimulation Surgery

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives One of the main challenges posed by the surgical deep brain stimulation (DBS) procedure is the successful targeting of the structures of interest and avoidance of side effects, especially in asleep surgery. Here, intraoperative motor evoked potentials (MEPs) might serve as tool to identify the pyramidal tract.
Petyo Nikolov   +7 more
wiley   +1 more source

Simple Fabrication Method of Needle‐Type Carbon‐Disk Microelectrodes Using Conductive Thermoplastics

open access: yesChemElectroChem
Carbon‐based microelectrodes are extensively used for sensing applications and space‐resolved electrochemistry experiments like scanning electrochemical microscopy (SECM).
Luiz F. Z. Felipe, Gabriel N. Meloni
doaj   +1 more source

Microelectrode-Based Electrochemical Impedance Determination of Brain-Derived Neurotrophic Factor in Aqueous Humor for Diagnosis of Glaucoma

open access: yes
The abundance of brain-derived neurotrophic factor (BDNF) in aqueous humor (AH) is an ideal biomarker for the diagnosis of glaucoma, a chronic progressive optic neuropathy and the most frequent cause of irreversible blindness.
Xin Xie (311744)   +5 more
core   +1 more source

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