Results 181 to 190 of about 52,627 (301)

Effects of nocturnal periodic breathing on sympathetic nerve activity and ventilatory control at high altitude: a randomised, crossover study

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the randomised crossover study investigating the effects of nocturnal periodic breathing (nPB) on sympathetic activity and ventilatory acclimatisation in hypobaric hypoxia equivalent to 4000 m altitude. Participants completed two 3‐day sojourns where nPB was inhibited by increasing inspiratory CO2 fraction ...
Johanna Roche   +13 more
wiley   +1 more source

Human‐derived cardiac‐neural microtissues reveal catecholaminergic polymorphic ventricular tachycardia is also a disease of the sympathetic neuron

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagram illustrating the proposed pathway in which regulatory defects might occur in sympathetic neurons derived from hiPSC in catecholaminergic polymorphic ventricular tachycardia (CPVT). Specifically, enhanced calcium transients appeared to derive from three sources: enhanced membrane excitability (due to loss of ...
Ni Li   +19 more
wiley   +1 more source

The contribution of peripheral nerves to the pleasure from scratching an itch: Evidence from a neuronopathy participant

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Acute itch was experimentally induced using histamine and cowage in control participants (with no neuronopathy) and in IW, a participant with a large‐fibre sensory neuronopathy resulting in the loss of Aβ afferent function below C3, at the same time as largely preserving Aδ and C‐fibre function.
Adarsh D. Makdani   +3 more
wiley   +1 more source

Longer action potential duration in the Purkinje network than in the ventricular myocardium delays retrograde activation of the human His‐Purkinje system

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Activation time (AT) maps from right ventricular apical pacing in a human ventricles model with longer action potential duration in the His‐Purkinje system (HPS) than in the myocardium (MYO). For pacing with a long S1S2 coupling interval (CI), the AT from the myocardial pacing site to the first AT of the HPS (ATMYO) is longer ...
Jason D. Bayer   +3 more
wiley   +1 more source

Author Correction: Implanted microelectrode arrays in reinnervated muscles allow separation of neural drives from transferred polyfunctional nerves. [PDF]

open access: yesNat Biomed Eng
Ferrante L   +8 more
europepmc   +1 more source

The ultrarapid delayed rectifier potassium current has important functional role in the repolarization reserve of canine and human ventricular muscle

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The ultrarapid delayed rectifier potassium current (IKur) has long been considered an atrial‐specific current with no functional role in the ventricles, despite evidence of its expression in ventricular myocytes. In the present study we challenged this prevailing concept and investigated the potential role of IKur in ventricular ...
Alaa Amin E. Abdelmagid   +17 more
wiley   +1 more source

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