Results 111 to 120 of about 62,682 (306)

Fabrication of High‐Density Multimodal Neural Probes Based on Heterogeneously Integrated CMOS

open access: yesAdvanced Science, EarlyView.
A chiplet‐based methodology democratizes active neural probe development on standard bulk CMOS services. This yields the first probe combining high‐density electrophysiology (416 electrodes) with calcium imaging (832 photodiodes) and complete on‐chip signal processing across 13 shanks.
Ju Hee Mun   +10 more
wiley   +1 more source

Characterization of the Neuroinflammatory Response to Thiol-ene Shape Memory Polymer Coated Intracortical Microelectrodes

open access: yesMicromachines, 2018
Thiol-ene based shape memory polymers (SMPs) have been developed for use as intracortical microelectrode substrates. The unique chemistry provides precise control over the mechanical and thermal glass-transition properties.
Andrew J. Shoffstall   +11 more
doaj   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

open access: yesAdvanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale   +6 more
wiley   +1 more source

The reactivity of platinum microelectrodes

open access: yesPhysical Chemistry Chemical Physics, 2016
Platinum ultramicroelectrodes exhibit lower reactivity towards surface sensitive reactions than macroelectrodes, typically due to (trace) contamination, making electrochemical characterization very important for a proper comparison.
Jacobse, L.   +2 more
openaire   +4 more sources

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

open access: yesAdvanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann   +11 more
wiley   +1 more source

A Signal-On Microelectrode Electrochemical Aptamer Sensor Based on AuNPs–MXene for Alpha-Fetoprotein Determination

open access: yesSensors
As a crucial biomarker for the early warning and prognosis of liver cancer diseases, elevated levels of alpha-fetoprotein (AFP) are associated with hepatocellular carcinoma and germ cell tumors.
Xiaoyu Su   +4 more
doaj   +1 more source

Accelerated Detection of Viral Particles by Combining AC Electric Field Effects and Micro-Raman Spectroscopy

open access: yesSensors, 2015
A detection method that combines electric field-assisted virus capture on antibody-decorated surfaces with the “fingerprinting” capabilities of micro-Raman spectroscopy is demonstrated for the case of M13 virus in water.
Matthew Robert Tomkins   +2 more
doaj   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

open access: yesAdvanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao   +3 more
wiley   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang   +3 more
wiley   +1 more source

Batch-fabricated full glassy carbon fibers for real-time tonic and phasic dopamine detection

open access: yesFrontiers in Bioengineering and Biotechnology
Dopamine (DA) is a critical neurotransmitter that is key in regulating motor functions, motivation, and reward-related behavior. Measuring both tonic (baseline, steady-state) and phasic (rapid, burst-like) DA release is essential for elucidating the ...
Umisha Siwakoti   +10 more
doaj   +1 more source

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