Results 151 to 160 of about 43,555 (289)

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

Comparing Electrochemical Performance of Thin-Film Ti-Pt Microelectrodes on Planar and Non-Planar Glass Substrates for Lab-on-a-Chip Applications. [PDF]

Micromachines (Basel)
Kołczyk-Siedlecka K, Szklarz Z, Vereshchagina E, Herbjørnrød A, Wittendorp P, Jain S, Żabiński P, Garbacz-Klempka A, Wójcik P.   +8 more
europepmc   +1 more source

Intermittent low‐intensity contractions cause a dissociation between maximal motor unit firing rates and changes in torque and contractile speed

Experimental Physiology, EarlyView.
Abstract The purpose was to test: (1) whether the decline in maximal motor unit (MU) firing rate is an invariable response when maximal voluntary contraction (MVC) torque is reduced following a submaximal muscle fatiguing task; and (2) whether fatigue‐induced slowing of contractile speed and firing rate decline are co‐dependent. Ten participants (three
Alexander M. Zero, Raaj A. Dudani, Jacob Fanous, Charles L. Rice   +3 more
wiley   +1 more source

The value of microelectrodes and microbipolar electrograms in premature ventricular complex mapping and ablation: The micro-PVC study. [PDF]

Heart Rhythm O2
Bergonti M, Szegedi N, Compagnucci P, Van Leuven O, Özkartal T, Caputo ML, Tanai E, Saenen J, Casella M, Conte G.   +9 more
europepmc   +1 more source

Is resting muscle sympathetic nerve activity related to peripheral or cerebrovascular haemodynamics at high altitude? A retrospective analysis

Experimental Physiology, EarlyView.
Abstract High‐altitude hypoxia elicits several profound physiological responses, including substantial increases in muscle sympathetic nerve activity (MSNA); however, the association of this heightened MSNA with cardiovascular and cerebrovascular haemodynamics remains unclear in lowlanders and indigenous highlander populations.
Ty J. A. MacDonald, Jenna C. McCrone, Christabel Osei‐Boateng, Connor D. Wideman, Samantha L. Tsioros, Joshua C. Tremblay, Alexander Patrician, Connor A. Howe, Geoff B. Coombs, Benjamin S. Stacey, Lydia L. Simpson, Mike Stembridge, Craig D. Steinback, Jonathan P. Moore, Travis D. Gibbons, Ryan L. Hoiland, Francisco Villafuerte, Gilbert Moralez, Philip N. Ainslie, Michael M. Tymko   +19 more
wiley   +1 more source

An artefact-resilient wide bandwidth bidirectional graphene neural interface. [PDF]

Nat Commun
Prokop M, Esparza-Iaizzo M, Masvidal-Codina E, Illa X, Codadu NK, Rathore D, Ria N, Kostarelos K, Del Corro E, Garcia-Cortadella R, Wykes RC, Guimerà-Brunet A, Garrido JA.   +12 more
europepmc   +1 more source

Pulmonary arterial mechanoreceptors mediate sustained sympathoexcitation during high altitude hypoxia in humans

Experimental Physiology, EarlyView.
Abstract Sympathetic nervous system activation is a hallmark of high‐altitude hypoxia, yet the afferent mechanisms remain incompletely defined. We examined the relative contributions of pulmonary arterial mechanoreceptors and carotid chemoreceptors – two excitatory pathways co‐activated by hypoxia – to sustained sympathoexcitation at altitude.
Michiel T. Ewalts, Lydia L. Simpson, Jack S. Talbot, Elliott J. Jenkins, Travis D. Gibbons, Connor A. Howe, Lauren E. Maier, Emily R. Vanden Berg, Alex M. Williams, Philip N. Ainslie, Samuel J. Oliver, Craig D. Steinback, Mike Stembridge, Jonathan P. Moore   +13 more
wiley   +1 more source

Single-neuron responses to neurostimulation: Insights for epilepsy. [PDF]

Neurotherapeutics
Cowan RL, Merricks EM, Davis TS, Rolston JD, Rahimpour S, Shofty B, Schevon CA, Smith EH.   +7 more
europepmc   +1 more source

Age‐related loss of hysteresis in the spontaneous vascular sympathetic baroreflex is associated with altered neural rather than mechanical control

Experimental Physiology, EarlyView.
Abstract The vascular sympathetic baroreflex is critical for stabilising blood pressure. A notable feature of this reflex is hysteresis, a directional asymmetry in responsiveness during rising versus falling pressure that is evident in young adults but attenuated in older age.
Guto Wyn Hughes, Denis J. Wakeham, Christopher J. A. Pugh, Zoe H. Adams, Rachel N. Lord, Jonathan P. Moore   +5 more
wiley   +1 more source

Shape-conformal porous frameworks for full coverage of neural organoids and high-resolution electrophysiology. [PDF]

Nat Biomed Eng
Liu N, Shiravi S, Jin T, Liu J, Zhu Z, Li J, Cheung I, Zhang H, Wang Y, Li Q, Xu Z, Zeng L, Quezada MJ, Villalobos A, Samei Y, Khanna S, Bao S, Wu M, Liang S, Cheng X, Lv Z, Maeng WY, Zhang Y, Luan H, Boppart SA, Huang Y, Zhang Y, Franz CK, Finan JD, Rogers JA.   +29 more
europepmc   +1 more source