Results 61 to 70 of about 30,710 (266)

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Engineering Neuronal Network Connectivity Through Precise and Scalable Electrical Modulation

Advanced Science, EarlyView.
This study presents a scalable all‐electrical method for precise neuronal‐circuit reconfiguration based on high‐density microelectrode arrays. By employing biologically inspired plasticity rules, targeted connectivity changes were successfully induced and quantified across diverse neuronal preparations.
Sreedhar S. Kumar, Yannaël Bossard, Rachel Sava, Tobias Gänswein, Lorenca Sadiraj, Jean‐Samuel Dupré, Manuel Schröter, J. Gray Camp, Fernando Cardes, Julian Bartram, Andreas Hierlemann   +10 more
wiley   +1 more source

Modification of Metal Microelectrodes with Vertical Graphene Structure for Enhanced Electrochemical Detection of Dopamine

Advanced Materials Interfaces
Detection of dopamine (DA) concentration can reflect important aspects of human brain health, including the nervous system and endocrine. Among various methods for detecting DA concentration, electrochemical detection is a promising method to allow in ...
Lukang Gao, Shuang Huang, Xiaotong Li, Zhengjie Liu, Xinshuo Huang, Yan Li, Hui‐jiuan Chen, Xudong Lin, Jing Liu, Xi Xie   +9 more
doaj   +1 more source

Microsphere‐Modulated Sensing‐in‐Energy Supercapacitor With Self‐Filtering Ultra‐Large Signal Under High‐g Shocks

Advanced Science, EarlyView.
To overcome severe signal oscillation under extreme impact conditions, this work presents a Sensing‐in‐Energy microdevice which integrates a MEMS inertial structure directly within a supercapacitor electrolyte cavity. Utilizing shock‐driven transient contact and electrolyte damping for signal self‐filtering, it achieves weak‐oscillation, large ...
Zhihao Zheng, Yiqun Wang, Kaiyou Liu, Shancheng Luan, Yajiang Yin, Xiaofeng Wang, Keren Dai, Zheng You   +7 more
wiley   +1 more source

Determinação da densidade de corrente de corrosão em meios de baixa condutividade: uso de microeletrodos para minimizar a queda ôhmica

Química Nova, 2011
The gravimetric and electrochemical tests are the most common techniques used in determining the corrosion rate. However, the use of electrochemical polarization is limited to electrolytes with sufficient conductivity for which Tafel curves are linear ...
Paulo César A. de Oliveira, Rodnei Bertazzoli   +1 more
doaj   +1 more source

In Vivo Electrochemical Monitoring of Safinamide Pharmacokinetics in the Brain Explores Its Correlation With Vision‐Related Neuronal Activity

Advanced Science, EarlyView.
An electrochemical platform based on differential pulse amperometry enables real‐time, selective tracking of safinamide pharmacokinetics in the living brain with high spatiotemporal resolution. When integrated with electrophysiology, this approach reveals that drug‐induced suppression of vision‐related neuronal activity provides mechanistic insight ...
Xiaoke Nan, Chuqi Li, Qianhe Dai, Junlan Zhou, Lijiao Cao, Yuying Liu, Jinger Chen, Meiping Xiong, Yuhang Jiang, Xianchan Li   +9 more
wiley   +1 more source

Scalable, Modular Three-Dimensional Silicon Microelectrode Assembly via Electroless Plating

Micromachines, 2018
We devised a scalable, modular strategy for microfabricated 3-D neural probe synthesis. We constructed a 3-D probe out of individual 2-D components (arrays of shanks bearing close-packed electrodes) using mechanical self-locking and self-aligning ...
Jörg Scholvin, Anthony Zorzos, Justin Kinney, Jacob Bernstein, Caroline Moore-Kochlacs, Nancy Kopell, Clifton Fonstad, Edward S. Boyden   +7 more
doaj   +1 more source

The reactivity of platinum microelectrodes

Physical Chemistry Chemical Physics, 2016
Platinum ultramicroelectrodes exhibit lower reactivity towards surface sensitive reactions than macroelectrodes, typically due to (trace) contamination, making electrochemical characterization very important for a proper comparison.
Jacobse, L., Raaijman, S.J., Koper, M.T.M.   +2 more
openaire   +4 more sources

Stretchable Microelectrode Arrays with Microneedles for Reliable Electrophysiological Recording of Human Heart and Brain Organoids

Advanced Science, EarlyView.
A stretchable 3D microelectrode array with microneedles (3D MN‐sMEA) enables stable, minimally destructive electrophysiological monitoring of 3D organoids. The wafer‐level stud‐bump bonding process facilitates high‐fidelity recordings of heart and cerebral organoids.
Eunyoung Jang, Saewoon Shin, Seul‐Gi Lee, Kiup Kim, Yoojeong Kim, Jun Sun, Il‐Joo Cho, Joseph A. Gogos, Jong‐Chan Park, C‐Yoon Kim, Hyunjoo J. Lee   +10 more
wiley   +1 more source

Characterization of the Neuroinflammatory Response to Thiol-ene Shape Memory Polymer Coated Intracortical Microelectrodes

Micromachines, 2018
Thiol-ene based shape memory polymers (SMPs) have been developed for use as intracortical microelectrode substrates. The unique chemistry provides precise control over the mechanical and thermal glass-transition properties.
Andrew J. Shoffstall, Melanie Ecker, Vindhya Danda, Alexandra Joshi-Imre, Allison Stiller, Marina Yu, Jennifer E. Paiz, Elizabeth Mancuso, Hillary W. Bedell, Walter E. Voit, Joseph J. Pancrazio, Jeffrey R. Capadona   +11 more
doaj   +1 more source