Results 91 to 100 of about 264,823 (308)

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

open access: yesAdvanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat   +11 more
wiley   +1 more source

Visible-light–triggered BMP-2 release from enzymatically crosslinked marine collagen–alginate hydrogel blends enhances osteogenesis in dental pulp stem cells

open access: yesFrontiers in Physiology
ObjectivesAchieving spatiotemporal control over osteoinductive signaling remains a key challenge in craniofacial tissue engineering. Conventional BMP-2 delivery from photocrosslinked hydrogels often leads to uncontrolled burst release and cytotoxic by ...
Francesco Torelli, Francesco Torelli
doaj   +1 more source

4D‐Printed Magneto‐Plasmonic Microrobots for Programmable Spatiotemporal De‐Icing

open access: yesAdvanced Functional Materials, EarlyView.
A 4D‐printing strategy is introduced to achieve programmable de‐icing devices. By aligning gold–magnetite nanofillers within a photosensitive resin, the printed structures exhibit dual magnetic and plasmonic functionalities, enabling precise spatio‐temporal ice removal through thermoplasmonic effects.
Amélie Pérot   +7 more
wiley   +1 more source

A novel microfluidic 3D platform for culturing pancreatic ductal adenocarcinoma cells: comparison with in vitro cultures and in vivo xenografts

open access: yesScientific Reports, 2017
The integration of microfluidics and cell biology has reached a significant milestone with the development of “organ-on-chips”, smart technological platforms that, once applied to the study of human diseases, such as cancer, might ultimately contribute ...
Meike Beer   +10 more
doaj   +1 more source

Integrated microfluidic tmRNA purification and real-time NASBA device for molecular diagnostics. [PDF]

open access: yes, 2008
We demonstrate the first integrated microfluidic tmRNA purification and nucleic acid sequence-based amplification (NASBA) device incorporating real-time detection.
Antonio J. Ricco   +48 more
core   +1 more source

Triplet‐Triplet Annihilation Enhances Photochemical Curing Contrast for Vat‐Based 3D Printing

open access: yesAdvanced Functional Materials, EarlyView.
Triplet–triplet annihilation photopolymerization (TTAP) resins enhance curing contrast for digital light processing (DLP) 3D printing compared to conventional Type I and II photopolymerizations at matched optical densities. By exploiting a superlinear initiation response, TTAP preserves fine details, allowing reliable fabrication of complex structures ...
Connor J. O'Dea   +2 more
wiley   +1 more source

Biomimetic and Biophysical Approach to Profile Metastatic Cancer Cell Migration [PDF]

open access: yes, 2018
Honors Research ScholarshipCancer metastasis is a complex process by which cells in a primary tumor acquire an aggressive phenotype, and travel to distant, secondary sites in the body.
Enders, Jacob
core  

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

open access: yesAdvanced Functional Materials, EarlyView.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source

Review of Recent Metamaterial Microfluidic Sensors

open access: yesSensors, 2018
Metamaterial elements/arrays exhibit a sensitive response to fluids yet with a small footprint, therefore, they have been an attractive choice to realize various sensing devices when integrated with microfluidic technology.
Ahmed Salim, Sungjoon Lim
doaj   +1 more source

Swelling‐Programmed Topographical Guidance for Dynamic Spheroid Self‐Assembly via a Mechanochemical Hydrogel Niche

open access: yesAdvanced Functional Materials, EarlyView.
A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy