Results 91 to 100 of about 5,481 (212)
ABSTRACT Type 1 Diabetes (T1D) is an autoimmune disorder marked by the immune‐mediated destruction of pancreatic β‐cells, resulting in insulin deficiency and dysregulated glucose control. Current therapies—such as insulin replacement and artificial pancreas systems—manage symptoms but fail to restore endogenous β‐cell function or halt disease ...
Fatemeh Sabet Sarvestani +4 more
wiley +1 more source
ABSTRACTBackgroundLow back pain remains the leading cause of disability worldwide, with intervertebral disc degeneration representing a major biological contributor. Although cell‐based therapies have shown promise in preclinical models, clinical translation has yielded modest and inconsistent outcomes.
Tynhinane Hamidouche +9 more
wiley +1 more source
Ribbon-shaped microgels as bioinks for 3D bioprinting of anisotropic tissue structures
Granular microgels are attractive bioinks for bioprinting due to their injectability, printability, modularity, and enhanced macroporosity compared to conventional nanoporous hydrogels.
Hung Pang Lee +9 more
doaj +1 more source
Structure Formation in Dairy Cheese and Plant‐Based Cheese Analogues: A Review
In this review, structure formation in dairy cheese and plant‐based cheese analogues is analyzed following a multi‐length scale perspective. Particular emphasis is placed on the distinction between bottom‐up assembly, characteristic of natural dairy cheese, and top‐down structuring, typical of processed cheese and cheese analogues.
Laurens J. Antuma +3 more
wiley +1 more source
Inspired by lung alveolar architecture, a dual‐templating strategy combining CO2 bubble and ice templating creates mechanically robust super‐macroporous hydrogels with highly interconnected transport pathways. The resulting material achieves 3.37× faster moisture sorption and 1.72× higher solar‐driven water release than single‐templated counterparts ...
Pan Huang +7 more
wiley +1 more source
Granular hydrogels are emerging as an important class of scaffolds for biomedical applications, due to their injectability and pore structure to support cellular infiltration.
Gabriel J. Rodriguez‐Rivera +11 more
doaj +1 more source
Structural Guidance in 3D Microgel‐in‐Hydrogel Systems to Improve Chondrogenesis
The Anisogel, an anisotropic microgel‐in‐hydrogel system, guides chondrogenic differentiation of human mesenchymal stromal cells (hMSCs) modulated by the alignment and size of anisometric microgels. Chondrogenic markers are upregulated in an in vitro model and guided tissue infiltration is enhanced in a semi‐orthopedic mouse model due to the physico ...
Julia Kamp +12 more
wiley +1 more source
Gellan gum fluid gel (FG) enables controlled ocular delivery of mesenchymal stromal cell (MSC)‐derived extracellular vesicles (EV). Its shear‐thinning, solid‐liquid‐solid rheology ensures prolonged ocular retention. Sustained MSC‐EV release (∼18% in 6 hrs) supports effective EV ocular delivery.
Seyedmohammad Moosavizadeh +7 more
wiley +1 more source
Neutron Reflectometry and Compression of Graded Hydrogel Surfaces
Highly‐entangled and covalently‐crosslinked hydrogels with thin and thick surface gel layers are compressed in neutron reflectometry experiments. Surface gel layer thickness dictates the extent to which the polymer network at the surface of a hydrogel collapses, while crosslinking chemistry, and therefore elastic modulus, impacts the pressure at which ...
Kathryn E. Shaffer +12 more
wiley +1 more source
A programmable plasmonic MOF–microgel SERS chip enables adaptive 3D interfacial coupling and energy level–wavelength dual selectivity on complex heterogeneous solids. It delivers nondestructive, spatially resolved identification and semiquantitative assessment of multiphase bronze corrosion from model stratigraphy to excavated artifacts.
Yahui Zhang +6 more
wiley +1 more source

