Results 41 to 50 of about 119,936 (297)

Whole-slide image analysis outperforms micrograph acquisition for adipocyte size quantification

Adipocyte, 2020
The distinction between biological processes of adipose tissue expansion is crucial to understanding metabolic derangements, but a robust method for quantifying adipocyte size has yet to be standardized.
Anne S Maguire, Lauren N Woodie, Robert L Judd, Douglas R Martin, Michael W Greene, Emily C Graff   +5 more
doaj   +1 more source

Cytogenetic, chromosome count optimization and automation of Neolamarckia cadamba (Rubiaceae) root tips derived from in vitro mutagenesis

Notulae Scientia Biologicae, 2021
Chromosome count is the only direct way to determine the number of chromosomes of a species. This study is often considered trivial that seldom described and discussed in detail.
Wei-Seng HO, Wee-Hiang ENG, Kwong-Hung LING   +2 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Micrograph of NMNH229901

, 2013
Low-quality light micrograph of 229901.
Martin R. Smith (3114384), Smith, Martin R.   +1 more
core   +1 more source

Scanning electron micrograph of blank Eudragit E100 microparticles.

, 2023
Scanning electron micrograph of blank Eudragit E100 microparticles.
Ruth N. Zadoks (8180979), Shazia Bashir (6946154), Nguyen Ngoc Phuoc (6889388), Tharangani Herath (14716912), Sudaxshina Murdan (7037300), Abdul Basit (174463)   +5 more
core   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Advancing electron microscopy using deep learning

JPhys Materials
Electron microscopy, a sub-field of microanalysis, is critical to many fields of research. The widespread use of electron microscopy for imaging molecules and materials has had an enormous impact on our understanding of countless systems and has ...
K Chen, A S Barnard
doaj   +1 more source

SEM micrograph of AMSNPs-MOR.

, 2016
SEM micrograph of AMSNPs-MOR.
Francisco Arriagada (758924), Claudio Olea-Azar (2081959), Germán Günther (316601), Francisco Mura (3331407), Santi Nonell (1303176), Javier Morales (316600), Olosmira Correa (3331404)   +6 more
core   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source