Kaempferol Attenuates Spaceflight-Associated Knee Cartilage Degradation by Targeting NOX4-Mediated Mitochondrial Dysfunction. [PDF]
Yin Y +23 more
europepmc +1 more source
Abstract A common misconception surrounding space exploration is that humanity's pursuit of interplanetary travel, such as missions to Mars, is an escape from Earth. In reality, this endeavour offers an invaluable opportunity to address critical biomedical challenges here at home.
Carina Kern, Tina Woods, Keith Siew
wiley +1 more source
Immune Cell Dysregulation in Hindlimb Unloading Mouse Model: Implications for Space Applications. [PDF]
Masoudi S +5 more
europepmc +1 more source
Abstract During weightlessness, the human neuro–muscular–skeletal system undergoes maladaptation to the microgravity environment. The European Space Agency (ESA) project NEX4EX, ‘Novel Exercise Hardware for Exploration’, developed an advanced multipurpose exerciser offering resistive (RES), plyometric (PLYO) and sensorimotor (SENSO) exercises.
Jonas Böcker +7 more
wiley +1 more source
Boundary cap neural crest stem cells exhibit remarkable resilience to environmental stressors associated with International Space Station mission. [PDF]
Fredriksson R +9 more
europepmc +1 more source
Effects of the space environment on articular cartilage homeostasis: a review. [PDF]
Ren Z, Huang H, Wang J.
europepmc +1 more source
Simulated microgravity induces a NOX-sensitive oxidative response that is attenuated by resveratrol in human endothelial cells. [PDF]
Giordo R +7 more
europepmc +1 more source
Blood flow restriction exercise during microgravity exposure in parabolic flight
Abstract This case report evaluates whether it is possible to perform blood flow restriction (BFR) exercise during exposure to microgravity. The objectives were three‐fold: (1) to determine if a personalised tourniquet system (PTS) hardware technology performs nominally and enables BFR exercise in microgravity; (2) to determine if BFR augments the ...
Yannick Laflamme +2 more
wiley +1 more source
Biological clocks and blood clots in space: circadian disruption-induced modulation of thrombosis risk. [PDF]
Ibrahim Z +6 more
europepmc +1 more source

