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Osteoclasts and Microgravity [PDF]

open access: yesLife, 2020
Astronauts are at risk of losing 1.0 to 1.5% of their bone mass for every month they spend in space despite their adherence to high impact exercise training programs and dietary regimens designed to preserve their musculoskeletal system. This loss is the result of microgravity-related impairment of osteocyte and osteoblast function and the consequent ...
exaly   +6 more sources
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Microgravity

Comprehensive Physiology, 2011
Abstract Gravity profoundly affects the overall mechanics of the respiratory system. Functional residual capacity, when measured in sustained microgravity, is intermediate to that present in the standing and supine postures in 1G, consistent with early modeling studies.
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Microgravity

Journal of Aerospace Sciences and Technologies, 2023
This project in its present form is the result of the question "Why Astronauts go to Space?" the initial idea was to find out the reason behind the same. After doing some research works finally the conclusion was that the astronauts get microgravity region in space, so that many experimental works may be done there which are not possible on earth due ...
Awaneesh Kumar, Kushal Singh
openaire   +1 more source

Microgravity and immune cells

open access: yesJournal of the Royal Society Interface, 2023
The microgravity environment experienced during spaceflight severely impaired immune system, making astronauts vulnerable to various diseases that seriously threaten the health of astronauts. Immune cells are exceptionally sensitive to changes in gravity and the microgravity environment can affect multiple aspects of immune cells through different ...
Chunmei Jiang   +2 more
exaly   +3 more sources

Osmosis and microgravity

Biochemical and Biophysical Research Communications, 1989
Abstract It is demonstrated that in the absence of buoyancy driven convection, as in microgravity, the osmotic process is modified considerably.
H A, Papazian, L W, Mason
openaire   +2 more sources

Microgravity as a model of ageing

Current Opinion in Clinical Nutrition and Metabolic Care, 2003
Longevity with good health and long-term survival in space are two of the many challenges that scientists face in the twenty-first century. Ageing and life in space are both associated with undesirable effects on normal physiological processes. This review will outline how the endocrine, metabolic, immune and musculoskeletal systems are affected by ...
BIOLO, GIANNI   +3 more
openaire   +6 more sources

Vestibulospinal Adaptation to Microgravity

Otolaryngology–Head and Neck Surgery, 1998
Human balance control is known to be transiently disrupted after spaceflight; however, the mechanisms responsible for postflight postural ataxia are still under investigation. In this report, we propose a conceptual model of vestibulospinal adaptation based on theoretical adaptive control concepts and supported by the results from a comprehensive study
openaire   +2 more sources

Growing tissues in microgravity

Nature Medicine, 1998
The possibility of creating three-dimensional differentiated tissue-like assemblies by culturing cells in microgravity, either in space or on the ground, offers research opportunities that may lead to the generation of replacement organs for transplantation, and for studying multicellular responses in toxicology, radiation biology, tumorigenesis, and ...
B R, Unsworth, P I, Lelkes
openaire   +2 more sources

Microgravity tissue engineering

In Vitro Cellular & Developmental Biology - Animal, 1997
Tissue engineering studies were done using isolated cells, three-dimensional polymer scaffolds, and rotating bioreactors operated under conditions of simulated microgravity. In particular, vessel rotation speed was adjusted such that 10 mm diameter x 2 mm thick cell-polymer constructs were cultivated in a state of continuous free-fall.
L E, Freed, G, Vunjak-Novakovic
openaire   +2 more sources

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