Results 61 to 70 of about 979 (187)

From Regeneration Failure to Functional Restoration: Unlocking the Neuronal‐Intrinsic Regenerative Capacity as a Therapeutic Frontier for Optic Neuropathy and Glaucoma

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
Optic neuropathy and glaucoma cause permanent visual deficits via retinal ganglion cell (RGC) loss and axon degeneration, affecting millions worldwide. Current treatments slow disease progression but cannot restore lost vision due to regeneration failure in adult RGCs.
Emma Beard   +4 more
wiley   +1 more source

Microinterventional system for robot-assisted gonioscopic surgery– technical feasibility and preclinical evaluation in synthetic eye models

open access: yesBMC Ophthalmology
Background Preclinical technical feasibility study of robot-assisted microinvasive glaucoma surgery using a novel ophthalmic robot-assisted surgery system.
Gautam Kamthan   +9 more
doaj   +1 more source

Bio-Interventional Cyclodialysis and Allograft Scleral Reinforcement for Uveoscleral Outflow Enhancement in Open-Angle Glaucoma Patients: One-Year Clinical Outcomes. [PDF]

open access: yes
BACKGROUND: To evaluate the one-year safety and effectiveness of bio-interventional cyclodialysis and scleral reinforcement in open-angle glaucoma (OAG) patients undergoing cataract surgery.
Ahmed, Iqbal   +7 more
core   +2 more sources

Impact of minimally invasive glaucoma surgery on the ocular surface and quality of life in patients with glaucoma [PDF]

open access: yes, 2023
Background: Minimally invasive glaucoma procedures are emerging as clinically effective and safe glaucoma management approaches; however, evidence regarding quality-of-life outcomes is limited.
Jones, L   +3 more
core  

Microinvasive Glaucoma Surgery—A New Chapter in Glaucoma Management [PDF]

open access: yesUS Ophthalmic Review, 2016
The continuous search for techniques and devices that lower the intraocular pressure without the complications associated with our gold standard trabeculectomy procedure has led to some promising developments in glaucoma surgery. The newly emerging technologies place improved patient safety as a priority.
openaire   +1 more source

Combined Microinvasive Glaucoma Surgery – A Review of the Literature and Future Directions

open access: yesSeminars in Ophthalmology, 2023
The use of microinvasive invasive glaucoma surgery (MIGS) in the treatment of glaucoma has increased exponentially over the last 10 years. However, practice patterns vary widely given the relative newness of these technologies. Some surgeons perform two or more MIGS simultaneously, such as those that target aqueous production and those that target ...
Derek D, Mai   +3 more
openaire   +2 more sources

Neuroprotective effects of resveratrol on retinal ganglion cells in glaucoma in rodents: A narrative review

open access: yesAnimal Models and Experimental Medicine, Volume 7, Issue 3, Page 195-207, June 2024.
Resveratrol (RES) exerts antioxidant and antiapoptotic effects on retinal ganglion cells (RGC) through various cellular and molecular mechanisms. First, RES has been found to protect RGCs from damage induced by oxidative stress and inflammation. It inhibits hypoxia‐induced RGC mortality by downregulating apoptosis and the production of ErbB2, a protein
Maryam Golmohammadi   +10 more
wiley   +1 more source

New Surgical Options in Glaucoma [PDF]

open access: yes, 2015
The treatment of glaucoma is undergoing constant change. In the last decade, there has been a surge of novel surgical options that aim to lower intraocular pressure while providing improved safety profiles compared to traditional incisional glaucoma ...
Damji, Karim F   +2 more
core   +2 more sources

Secondary glaucoma: Toward interventions based on molecular underpinnings

open access: yesWIREs Mechanisms of Disease, Volume 16, Issue 1, January/February 2024.
Proposed effects of melatonin on anterior segment cells. Melatonin is a potent melanogenesis suppressor acting by inhibiting α‐MSH effects. As a result, melanin‐containing granules aggregate around the nucleus. Melatonin is a potent antioxidant capable of scavenging ROS/RNS generated by UV radiation (UV‐R).
Anna Mueller   +4 more
wiley   +1 more source

Development of a drug-eluting microstent for micro-invasive glaucoma surgery

open access: yesCurrent Directions in Biomedical Engineering, 2018
Glaucoma represents the leading cause of irreversible blindness worldwide. Therapeutic approaches are based on the lowering of intraocular pressure (IOP).
Siewert Stefan   +10 more
doaj   +1 more source

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