Results 371 to 380 of about 36,831 (386)

Effect of Microneedle Geometry and Supporting Substrate on Microneedle Array Penetration into Skin

Journal of Pharmaceutical Sciences, 2013
Microneedles are being fast recognized as a useful alternative to injections in delivering drugs, vaccines, and cosmetics transdermally. Owing to skin's inherent elastic properties, microneedles require an optimal geometry for skin penetration. In vitro studies, using rat skin to characterize microneedle penetration in vivo, require substrates with ...
Kochhar, J.S., Quek, T.C., Soon, W.J., Choi, J., Zou, S., Kang, L.   +5 more
openaire   +3 more sources

Microneedling of the Scalp

2020
Scalp microneedling is a current treatment option that has been considered excellent when used in combination with the clinical treatment of alopecias.
Renan Minotto, Liliam Dalla Corte
openaire   +2 more sources

Fabrication of Microneedles

2017
Delivery of active pharmaceutical ingredients through transdermal route has been limited due to the excellent barrier properties of the stratum corneum (SC) of the skin. Only drugs with very specific physicochemical properties (molecular weight < 500 daltons, adequate lipophilicity and low melting point) can be successfully administered transdermally ...
Ahlam Zaid Alkilani, Karen Mooney, Hannah McMillan, Ryan F. Donnelly, Thakur Raghu Raj Singh   +4 more
openaire   +2 more sources

Microneedling and Drug Delivery

2021
Drug delivery assisted by microneedling allows increasing the permeation of drugs with the use of a minimally invasive technique. Microneedling produces micropunctures that can be used as transportation routes of substances through biologic membranes, such as the stratum corneum.
Clarissa Prieto Herman Reinehr, Célia Luiza Petersen Vitello Kalil   +1 more
openaire   +2 more sources

An integrated wearable microneedle array for the continuous monitoring of multiple biomarkers in interstitial fluid

Nature Biomedical Engineering, 2022
Farshad Tehrani, H. Teymourian, Brian L. Wuerstle, Jonathan Kavner, Ravi Patel, Allison Furmidge, Reza Aghavali, Hamed Hosseini-Toudeshki, Christopher Brown, Fangyu Zhang, Kuldeep Mahato, Zhengxing Li, A. Barfidokht, Lu Yin, Paul Warren, Nickey Huang, Zina Patel, P. Mercier, Joseph Wang   +18 more
semanticscholar   +1 more source

Microneedle biomedical devices

Nature Reviews Bioengineering, 2023
M. Zheng, Tao Sheng, Jicheng Yu, Zhen Gu, Chenjie Xu   +4 more
semanticscholar   +1 more source

Microneedling with Biologicals

Facial Plastic Surgery Clinics of North America, 2018
Microneedling is a popular and cost-effective treatment with little down time. The application of topical agents to enhance outcomes is common practice. Microchannels created with nonthermal needling close at 4 hours to 6 hours due to fibrin plugs.
openaire   +2 more sources

Microneedle-based biosensing

Nature Reviews Bioengineering, 2023
Lalitkumar K. Vora, A. Sabri, Peter E. McKenna, Achmad Himawan, A. Hutton, Usanee Detamornrat, A. Paredes, E. Larrañeta, Ryan F. Donnelly   +8 more
semanticscholar   +1 more source

Polymer microneedles

A method for producing microneedles. The method including disposing a first layer of a radiation sensitive polymer on to a working surface and selectively irradiating the first layer such that the first layer has at least one irradiated region and at least one non-irradiated region.
Berenschot, Johan W., de Boer, Meint J., Boom, G.   +2 more
openaire  

Microneedle, microneedle array and production method therefor

The present invention provides a microneedle, comprising a shaft of a monocrystalline material having at least three walls which are formed by a crystal plane of the monocrystalline material; and a tip connected to an end of the shaft comprising at least three walls which are formed by a crystal plane of the material. The material is preferably silicon.
Berenschot, Johan W., Tas, Niels Roelof, de Boer, Meint J.   +2 more
openaire