Results 101 to 110 of about 891,133 (254)

Taxonomic description of Micromonospora reichwaldensis sp. nov. and its biosynthetic and plant growth-promoting potential

Microbiology Spectrum
Micromonospora strains proved to be a model organism for drug discovery and plant growth promotion (PGP). Strain DSM 115977 T was subjected to polyphasic taxonomic analysis and genome mining for biosynthetic gene clusters and PGP-associated genes in ...
Imen Nouioui, Alina Zimmermann, Juan Pablo Gomez Escribano, Marlen Jando, Gabriele Pötter, Meina Neumann-Schaal, Yvonne Mast   +6 more
doaj   +1 more source

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

Advanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li, Ka Man Ng, Xingsheng Shu, Xiaoxue Chai, Kai Yau Wong, Gopesh Srivastava, Anthony T.C. Chan, Wai Yee Chan, Qian Tao   +8 more
wiley   +1 more source

Optimizing DNA and mRNA vaccine against Human metapneumovirus structural proteins based on rationally designed multi-epitope construct

Scientific Reports
Nucleic acid-based vaccines have emerged as powerful tools in combating both emerging and re-emerging viral pathogens. Among these, Human metapneumovirus (HMPV) is a respiratory pathogen that predominantly affects children, immunocompromised individuals,
Leonardo Pereira de Araújo, Laura Leone da Silva, André Luiz Caliari Costa, Guilherme Landim de Rezende, Evandro Neves Silva, Patrícia Paiva Corsetti, Leonardo Augusto de Almeida   +6 more
doaj   +1 more source

Electroactive Microbial Consortium of Bacillus, Lysinibacillus, and Lactococcus for Enhanced Wastewater Treatment and Bioelectricity Generation

Biology
Microbial fuel cell (MFC) technology represents a promising bioelectrochemical approach for the simultaneous generation of electricity and treatment of high-strength wastewater. However, the performance of MFCs strongly depends on the metabolic potential
Aliya Temirbekova, Zhanar Tekebayeva, Timoth Mkilima, Kamshat Kulzhanova, Zhadyrassyn Nurbekova, Aslan Temirkhanov, Kulyash Meiramkulova, Zhandarbek Bekshin, Akhan Abzhalelov   +8 more
doaj   +1 more source

Biofilm‐Binding Phages Enhance Biofilm Eradication by Synergistic Photothermal and Photodynamic Therapy

Advanced Science, EarlyView.
Engineered phage‐based trifunctional nanofibers are developed for synergistic biofilm eradication. Biofilm‐binding phages, armed with AuNPs and TCPP, serve as both warheads and scaffolds, endowing the phototherapy agents with biofilm‐anchoring ability. Upon light irradiation, AuNPs induce photothermal therapy, while TCPP generates 1O2 for photodynamic ...
Ying Cao, Tao Yang, Rui Wang, Hui‐Da Li, Xiao‐Yu Zhang, Feng Cheng, Ying Liu, Jian‐Hua Wang, Ting Yang, Chuanbin Mao   +9 more
wiley   +1 more source

Chasmophyte associated stress tolerant bacteria confer drought resilience to chickpea through efficient nutrient mining and modulation of stress response

Scientific Reports
In the present study, ten (10) selected bacteria isolated from chasmophytic wild Chenopodium were evaluated for alleviation of drought stress in chickpea. All the bacterial cultures were potential P, K and Zn solubilizer.
Sudipta Das, Hillol Chakdar, Adarsh Kumar, Rajni Singh, Anil Kumar Saxena   +4 more
doaj   +1 more source

Untargeted metabolomic profiling and genome mining of endophytic Stenotrophomonas maltophilia strain 3A reveal a rich source of bioactive secondary metabolites

Frontiers in Microbiology
The changing climate has posed several constraints in agricultural productivity. The losses from the diseases like bacterial wilt caused by Ralstonia solanacearum are a major threat to tomato cultivation, however, the management is still difficult.
Pramod Kumar Sahu, Krishna Nanda Dhal, Nakul Kale, Amrita Gupta, Nidhi Rai, Deepak Singla, Alok Kumar Srivastava   +6 more
doaj   +1 more source

The effect of smoking on caries-related microorganisms

, 2019
Introduction Epidemiological studies have shown a close relationship between smoking and dental caries. Bacteria are one of the essential factors of caries formation. The imbalance of cariogenic bacteria and commensal bacteria in dental plaque results in
Jiayi Wu, Mingyun Li^#, Ruijie Huang^#   +2 more
core   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets

Communications Biology
Predicting prokaryotic phenotypes—observable traits that govern functionality, adaptability, and interactions—holds significant potential for fields such as biotechnology, environmental sciences, and evolutionary biology.
Julia Koblitz, Lorenz Christian Reimer, Rüdiger Pukall, Jörg Overmann   +3 more
doaj   +1 more source