Results 51 to 60 of about 4,963 (215)

Erythrocyte-derived microparticles supporting activated protein C-mediated regulation of blood coagulation. [PDF]

PLoS ONE, 2014
Elevated levels of erythrocyte-derived microparticles are present in the circulation in medical conditions affecting the red blood cells. Erythrocyte-derived microparticles expose phosphatidylserine thus providing a suitable surface for procoagulant ...
Ruzica Livaja Koshiar, Sofia Somajo, Eva Norström, Björn Dahlbäck   +3 more
doaj   +1 more source

Anti‐Inflammatory and Neuroactive Effects of Polymer‐Coated Iron Oxide Nanoparticles Functionalized With Interleukin 4 for Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez, Paloma Lozano‐Picazo, María de Lamo‐Atencia, Andrea Ferreras, Esther Benayas‐Martín, Elena Fernández‐López, Marina Sánchez‐Petidier, Verónica Barranco‐Maresca, Víctor Caz, Anne des Rieux, Juliana M. Rosa, María del Puerto Morales, María C. Serrano   +12 more
wiley   +1 more source

Synergistic optimization of microstructures and properties of electrodeposited Ni–CeO2 composite coatings with CeO2 microparticles and CeO2 nanoparticles

Journal of Materials Research and Technology
The synergistic mechanism of microparticles and nanoparticles on optimizing microstructures homogeneity and enhancing microhardness and corrosion resistance of mixed coatings was deeply researched by co-electrodepositing CeO2 microparticles and CeO2 ...
Shuxin You, Shilong Xing, Chuanhai Jiang
doaj   +1 more source

Microparticles engineered to highly express peroxisome proliferator-activated receptor-γ decreased inflammatory mediator production and increased adhesion of recipient monocytes.

PLoS ONE, 2014
Circulating blood microparticles are submicron vesicles released primarily by megakaryocytes and platelets that act as transcellular communicators.
Julie Sahler, Collynn F Woeller, Richard P Phipps   +2 more
doaj   +1 more source

Microparticles in Angiogenesis [PDF]

Circulation Research, 2011
Considered during the past decades as cell dust, microparticles are now deemed true biomarkers and vectors of biological information between cells. Depending on their origin, the composition of microparticles varies and the subsequent message transported by them, such as proteins, mRNA, or miRNA, can differ. Recent studies have described microparticles
Martinez, Maria Carmen, Andriantsitohaina, Ramaroson   +1 more
openaire   +3 more sources

Magnetoactive Hydrogels to Probe Curvature‐Directed Endothelial Cell Mechanosensing

Advanced Healthcare Materials, EarlyView.
This work establishes a platform to investigate local curvature as a regulator of endothelial mechanosensing independent of shear stress. Magnetoactive hydrogels enable on‐demand curvature of endothelial monolayers to reproduce tortuosity quantified by clinically established metrics.
Avinava Roy, Grace K. Hinds, Joshua Yu‐Chung Liu, Ziqian Yang, Rishab Yanala, Arina E. Velieva, Claudia Loebel   +6 more
wiley   +1 more source

Optimizing Prednisolone Loading into Distiller’s Dried Grain Kafirin Microparticles, and In vitro Release for Oral Delivery

Pharmaceutics, 2017
Kafirin microparticles have potential as colon-targeted delivery systems because of their ability to protect encapsulated material from digestive processes of the upper gastrointestinal tract (GIT).
Esther T. L. Lau, Stuart K. Johnson, Barbara A. Williams, Deirdre Mikkelsen, Elizabeth McCourt, Roger A. Stanley, Ram Mereddy, Peter J. Halley, Kathryn J. Steadman   +8 more
doaj   +1 more source

Bone Organoids Across the Development‐to‐Remodeling Continuum: From Tissue Formation to Functional Competence and Translation

Advanced Healthcare Materials, EarlyView.
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang, Haijia Xu, Xiangzhong Liu, Yi Yang, Zhanghua Li   +4 more
wiley   +1 more source

Microparticles as Potential Biomarkers of Cardiovascular Disease

Arquivos Brasileiros de Cardiologia, 2015
Primary prevention of cardiovascular disease is a choice of great relevance because of its impact on health. Some biomarkers, such as microparticles derived from different cell populations, have been considered useful in the assessment of cardiovascular ...
Carolina Nunes França, Maria Cristina de Oliveira Izar, Jônatas Bussador do Amaral, Daniela Melo Tegani, Francisco Antonio Helfenstein Fonseca   +4 more
doaj   +1 more source

Neuronal Uptake of Nano‐Sized PMMA Orthopedic Wear Particles in a Compartmentalized Microfluidic Model Revealed by Label‐Free Confocal Raman Microscopy

Advanced Healthcare Materials, EarlyView.
Nano‐sized orthopedic implant‐derived particles interact with sensory neurons, with poly(methyl methacrylate) (PMMA)‐associated signal detected in neuronal somata following selective axonal exposure in compartmentalized microfluidic cultures. Label‐free confocal Raman microscopy provides complementary chemical evidence of PMMA‐associated material in ...
Marina Couto, Ana Carolina Monteiro, Maria Gomez‐Lazaro, Cristina Ribeiro, Estrela Neto, Daniela Pereira de Vasconcelos, Meriem Lamghari   +6 more
wiley   +1 more source