Results 11 to 20 of about 449 (113)

Targeted therapy of advanced parathyroid carcinoma guided by genomic and transcriptomic profiling

Molecular Oncology, Volume 17, Issue 7, Page 1343-1355, July 2023., 2023
Our case study on advanced parathyroid carcinoma using whole genome and transcriptome sequencing improved our understanding of the molecular pathogenesis of the disease by identifying a relevant contribution of the APOBEC signatures SBS2 and SBS13 to the mutational process, as well as a MUTHY heterozygous germline mutation as a potential predisposing ...
Maria‐Veronica Teleanu, Carmina T. Fuss, Nagarajan Paramasivam, Sebastian Pirmann, Andreas Mock, Christoph Terkamp, Stefan Kircher, Laura‐Sophie Landwehr, Christina Lenschow, Nicolas Schlegel, Albrecht Stenzinger, Arne Jahn, Martin Fassnacht, Hanno Glimm, Daniel Hübschmann, Stefan Fröhling, Matthias Kroiss   +16 more
wiley   +1 more source

Recent Progress in Genetics and Epigenetics Research on Diabetic Nephropathy in Malaysia

Journal of Diabetes Research, Volume 2023, Issue 1, 2023., 2023
Diabetic nephropathy is a multifactorial disease. Gene susceptibility, as well as environmental exposure, plays an important role in disease progression. Malaysia is reported to be among the world’s second‐fastest‐growing rates of kidney failure. Diabetic nephropathy has become the main cause of end‐stage renal disease in Malaysia.
Norhashimah Abu Seman, Siti Haslina Othman, Luis D′Marco   +2 more
wiley   +1 more source

Caracterización genética de la oveja Pelibuey de México usando marcadores microsatélites

Revista Mexicana de Ciencias Pecuarias, 2021
El objetivo fue caracterizar genéticamente 23 subpoblaciones de oveja Pelibuey de México y un rebaño cubano mediante nueve marcadores microsatélites. En el análisis por iniciadores, se observaron 99 alelos y un contenido de información polimórfica (PIC ...
Cecilio Ubaldo Aguilar Martínez, Bertha Espinoza Gutiérrez, José Candelario Segura Correa, José Manuel Berruecos Villalobos, Javier Valencia Méndez, Antonio Roldán Roldán   +5 more
doaj   +1 more source

Addressing the variation in adjuvant chemotherapy treatment for colorectal cancer: Can a regional intervention promote national change?

International Journal of Cancer, Volume 148, Issue 4, Page 845-856, 15 February 2021., 2021
Abstract Analysis of routine population‐based data has previously shown that patterns of surgical treatment for colorectal cancer can vary widely, but there is limited evidence available to determine if such variation is also seen in the use of chemotherapy.
John C. Taylor, Daniel Swinson, Jenny F. Seligmann, Rebecca J. Birch, Alice Dewdney, Victoria Brown, Joanna Dent, Hannah L. Rossington, Philip Quirke, Eva J. A. Morris, YCR BCIP Study Group   +10 more
wiley   +1 more source

Genetic diversity of native potatoes (Solanumspp.) conserved in landraces from Peru

Revista Peruana de Biología, 2014
This paper analyzes the genetic diversity of 79 accessions of native potato varieties (Solanum spp.) using 18 microsatellite markers. A random sample from Ayacucho, Cajamarca, Cusco, Huancavelica and Puno from "chacras" of farmers who collaborated with ...
Julián Soto, Tulio Medina, Yeny Aquino, Rolando Estrada   +3 more
doaj   +1 more source

Heterologous microsatellite-based genetic diversity in blue mussel (Mytilus chilensis) and differentiation among localities in southern Chile

Latin American Journal of Aquatic Research, 2015
Mussels (Mytilus spp.) are one of the most cultivated and commercialized bivalves in southern Chile; culture is currently supplied almost entirely from wild-caught seed obtained from relatively few collection centers.
María Angélica Larraín, Nelson F Díaz, Carmen Lamas, Carla Uribe, Felipe Jilberto, Cristián Araneda   +5 more
doaj   +1 more source

Estructura genética contrastante en dos especies codistribuidas de peces de agua dulce que habitan sistemas marcadamente estacionales

Revista Mexicana de Biodiversidad, 2009
DADA LA NATURALEZA ESTACIONAL DE ECOSISTEMAS COMO CENOTES PERMANENTES Y HUMEDALES TEMPORALES, SU FAUNA ÍCTIOLÓGICA EXPERIMENTA PROCESOS LOCALES ANUALES DE EXTINCIÓN Y COLONIZACIÓN, CON GRANDES FLUCTUACIONES EN EL TAMAÑO POBLACIONAL.
LUIS ZAMBRANO, ALIET ROJAS SANTOYO, ANGÉLICA HERNÁNDEZ VALDÉZ, ELLA VÁZQUEZ DOMÍNGUEZ   +3 more
doaj   +1 more source

Evaluation of the genetic variability of tamarillo (Solanum betaceum Cav.) crops in three provinces of Ecuador through microsatellite markers

ACI Avances en Ciencias e Ingenierías, 2009
El presente trabajo determinó el nivel de diversidad genética existente en varios cultivos de tomate de árbol (Solanum betaceum) de las provincias de Imbabura, Tungurahua y Pichincha, mediante el uso de marcadores microsatélites.
Nicolás Peñafiel L., Venancio S. Arahana B., María de Lourdes Torres P.   +2 more
doaj   +1 more source

Diversidad genética en poblaciones de Pinus remota (Pinaceae) del Noreste de México: evidencias de declinamiento demográfico histórico

Acta Botanica Mexicana, 2021
Métodos: El estudio se realizó en siete poblaciones representativas de su distribución natural en México, con muestras de acículas de 112 árboles analizadas con cinco microsatélites de núcleo.
Aridahí González Jiménez, Patricia Delgado Valerio, Agustín Molina Sánchez, Celestino Flores López, Juan Pablo Vargas Gutiérrez, J. Jesús García Magaña   +5 more
doaj   +1 more source

Caracterización de la diversidad genética de cultivares comerciales de heliconias en el centro occidente de Colombia

Agronomía Costarricense, 2018
La familia Heliconiaceae tiene un solo género, Heliconia L., con aproximadamente 250 especies. Debido al colorido de sus brácteas son muy usadas para fines ornamentales presentando una creciente comercialización en el mercado internacional, lo que ha ...
Marta Leonor Marulanda, Liliana Isaza, Paola Andrea López   +2 more
doaj   +1 more source