Results 101 to 110 of about 277,529 (354)

Content-Based Microscopic Image Retrieval System for Multi-Image Queries [PDF]

, 2012
WOS: 000305979500026PubMed ID: 22311866In this paper, we describe the design and development of a multitiered content-based image retrieval (CBIR) system for microscopic images utilizing a reference database that contains images of more than one disease.
Gürcan, Metin N., Akakin, Hatice Çınar   +1 more
core   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

Novel Approach Using Echo State Networks for Microscopic Cellular Image Segmentation

, 2016
International audienceThis paper concentrates on the use of Echo State Networks (ESNs), an effective form of reservoir computing, to improve microscopic cellular image seg-mentation.
Meftah, Boudjelal, Lézoray, Olivier, Benyettou, A.   +2 more
core   +1 more source

Mueller matrix polarization interferometry of optically anisotropic architectonics of biological tissue object fields: the fundamental and applied aspects

Frontiers in Physics
The presented results concern the diagnostic application of vector-parameter polarization mapping and polarization-interference phase scanning applied to layered azimuths and ellipticity polarization maps obtained with the help of digital holographic ...
Alexander Ushenko, Alexander Ushenko, Alexander Dubolazov, Jun Zheng, Oxana Bakun, Mykhaylo Gorsky, Yuriy Ushenko, Olexandra Litvinenko, Ivan Gordey, Chen Zhebo, Valeriy Sklyarchuk   +10 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Review of Microscopic Image Processing techniques towards Malaria Infected Erythrocyte Detection from Thin Blood Smears

, 2017
In order to diagnose malaria, the test that has traditionally been conducted is the gold standard test. The process mainly entails the preparation of a blood smear on glass slide, staining the blood and examining the blood through the use of a microscope
Md. Jaffar Sadiq
core  

Full-field evaluation of the onset of microplasticity in a steel specimen [PDF]

, 2009
This work deals with the study of the local onset of microplasticity in a steel specimen under tensile test through the use of a full-field strain measurement method at the micrometric scale.
Moulart, Raphaël, Rotinat, René, Pierron, Fabrice   +2 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Automated Detection of Canine Babesia Parasite in Blood Smear Images Using Deep Learning and Contrastive Learning Techniques

Parasitologia
This research introduces a novel method that integrates both unsupervised and supervised learning, leveraging SimCLR (Simple Framework for Contrastive Learning of Visual Representations) for self-supervised learning along with different pre-trained ...
Dilip Kumar Baruah, Kuntala Boruah, Nagendra Nath Barman, Abhijit Deka, Arpita Bharali, Lukumoni Buragohain   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source