Results 131 to 140 of about 7,676,720 (331)

Super-Resolution Correlative Light and Electron Microscopy (SR-CLEM) Reveals Novel Ultrastructural Insights Into Dendritic Cell Podosomes

Frontiers in Immunology, 2018
Podosomes are multimolecular cytoskeletal structures that coordinate the migration of tissue-resident dendritic cells (DCs). They consist of a protrusive actin-rich core and an adhesive integrin-rich ring that contains adaptor proteins such as vinculin ...
Ben Joosten, Marieke Willemse, Marieke Willemse, Jack Fransen, Jack Fransen, Alessandra Cambi, Koen van den Dries   +6 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Oral squamous cell carcinoma detection using EfficientNet on histopathological images

Frontiers in Medicine
IntroductionOral Squamous Cell Carcinoma (OSCC) poses a significant challenge in oncology due to the absence of precise diagnostic tools, leading to delays in identifying the condition. Current diagnostic methods for OSCC have limitations in accuracy and
Eid Albalawi, Arastu Thakur, Mahesh Thyluru Ramakrishna, Surbhi Bhatia Khan, Surbhi Bhatia Khan, Suresh SankaraNarayanan, Badar Almarri, Theyazn Hassn Hadi   +7 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Imaging acoustic waves in microscopic wedges

New Journal of Physics, 2014
Using an ultrafast optical technique we image near-gigahertz flexural acoustic waves propagating in a thin gold wedge deposited on an ultrathin silicon nitride slab.
Motonobu Tomoda, Shinnosuke Matsueda, Paul H Otsuka, Osamu Matsuda, Istvan A Veres, Vitalyi E Gusev, Oliver B Wright   +6 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

High-Definition Optical Coherence Tomography for the in vivo Detection of Demodex Mites [PDF]

, 2012
Background: Demodex mites are involved in different skin diseases and are commonly detected by skin scrape tests or superficial biopsies. A new high-definition optical coherence tomography (HD-OCT) with high lateral and axial resolution in a horizontal ...
Sattler, E., Maier, T., Ruzicka, Thomas, Braun-Falco, M., Berking, C.   +4 more
core   +1 more source

Research progress of optical monitoring technologies for membrane fouling

Gongye shui chuli
Optical monitoring technologies can be used to monitor membrane fouling in real-time and online with the in-situ, fast and nondestructive advantages, which are of great significance for the in-depth understanding of membrane fouling and the optimization ...
REN Zhijun, BAI Ying, WANG Qiuwen, HAN Jinlong, LIU Xiaoyang   +4 more
doaj   +1 more source

CENTIMETER-DEEP TISSUE FLUORESCENCE MICROSCOPIC IMAGING [PDF]

, 2016
Fluorescence microscopic imaging in centimeter-deep tissue has been highly sought-after for many years because much interesting in vivo micro-information—such as microcirculation, tumor angiogenesis, and cancer metastasis—may deeply locate in tissue ...
Cheng, Bingbing
core   +1 more source

Data for Microscopic magnetic field imaging with hot atoms via single-pixel imaging [PDF]

This folder contains the data required to reproduce the plots in the manuscript Microscopic magnetic field imaging with hot atoms via single-pixel imaging, arXiv:2508.13869, accepted by Optics ...
Weidner, Carrie, Torre, Cyril
core   +1 more source