Results 201 to 210 of about 7,676,720 (331)

Electron microscopic imaging and NanoSIMS investigation on physiological responses of Aspergillus niger under Pb(II) and Cd(II) stress. [PDF]

Front Bioeng Biotechnol, 2022
Pan S, Li Z, Wang J, Li X, Meng L, Chen Y, Su M, Li Z.   +7 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Single-Shot Sub-Picosecond Ultrafast Microscopic Imaging Utilizing Spatial-Frequency Multiplexing for Ultrafast Laser-Induced Plasma Visualization. [PDF]

Nanomaterials (Basel)
Li H, Li Y, Shang Y, Yue M, Luo D, Xue Y, Gao G, Tian J.   +7 more
europepmc   +1 more source

Deep Learning and Microscopic Imaging in the Nursing Process of Neurosurgery Operation.

J Healthc Eng, 2022
Jiang W.
europepmc   +1 more source

Light and electron microscopic imaging of synaptic vesicle endocytosis at mouse hippocampal cultures. [PDF]

STAR Protoc, 2022
Shi B, Wu XS, Cordero NP, Moreira SL, Wu LG.   +4 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Safirinium Fluorescent "Click" Molecular Probes: Synthesis, CuAAC Reactions, and Microscopic Imaging. [PDF]

Molecules
Kasza P, Szafrański PW, Fedorowicz J, Krzysztofiak F, Pociecha K, Wójcik-Pszczoła K, Koczurkiewicz-Adamczyk P, Kępczynski M, Sączewski J, Zajdel P, Cegła M.   +10 more
europepmc   +1 more source

MO-SOD: Micro-Oxidation Small Object Detection Model for Oxygen-Free Copper Surfaces Based on Microscopic Imaging System. [PDF]

ACS Omega, 2023
Li Q, Zhang T, Yang M, Guo X, Chen H, Fan S.   +5 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Using microscopic imaging and ensemble deep learning to classify the provenance of archaeological ceramics. [PDF]

Sci Rep
Wang Q, Xiao X, Liu Z.
europepmc   +1 more source