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Microscopy

Pancreatology, 2009
Microscopy employs the use of microscopes, which are instruments designed to produce magnified visual or photographic images of objects too small to be seen with the naked eye. The goal of the microscope is to accomplish three tasks, namely produce a magnified image of the specimen, separate the details in the image, and render the details visible to ...
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Fluorescence Microscopy

Current Protocols in Immunology, 1998
AbstractAbsorption of energy as light by some molecules and emission of energy as fluorescence can occur only at certain wavelengths, which are characteristic for a given molecule (fluorophore). Fluorescence microscopes are equipped to observe the fluorescence of one or more specific fluorophores to localize specific molecules and analyzed cellular ...
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Biological microscopy: the emergence of digital microscopy

Current Opinion in Biotechnology, 1993
The past few years have seen a tremendous renaissance in biological optical microscopy, mainly as a result of the application of digital image processing and video imaging techniques. We review recent developments in microscopy that are permitting unprecedented views of biological structure and function.
Ivins, Jonathan K.   +2 more
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microscopy and cryo-microscopy

2000
Abstract Characterization of the DNA curvature and flexibility, intrinsic or induced by protein, re-mains controversial and depends on the method used. Such an analysis is even more difficult with respect to the confom1ational changes in DNA induced by non-specific binding proteins such as histone-like proteins.
Eric Le Cam, Etienne Delain
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Acoustic Microscopy by Atomic Force Microscopy

Applied Physics Letters, 1994
We have constructed an atomic force microscope enabling one to image the topography of a sample, and to monitor simultaneously ultrasonic surface vibrations in the MHz range. For detection of the distribution of the ultrasonic vibration amplitude, a part of the position-sensing light beam reflected from the cantilever is directed to an external knife ...
U. Rabe, W. Arnold
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Photoionization Microscopy

Physical Review Letters, 2002
We present the first experimental results of a technique called photoionization microscopy. Photoelectrons ejected in threshold photoionization of Xe are detected in a velocity map imaging apparatus, and interferences between various trajectories by which the electron moves from the atom to the detector are observed.
C, Nicole   +4 more
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Correlated Light Microscopy and Electron Microscopy

2012
Understanding where, when, and how biomolecules (inter)act is crucial to uncover fundamental mechanisms in cell biology. Recent developments in fluorescence light microscopy (FLM) allow protein imaging in living cells and at the near molecular level. However, fluorescence microscopy only reveals selected biomolecules or organelles but not the (ultra ...
Sjollema, Klaas A.   +4 more
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