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Electron Microscopy of Bone

2013
Mineralized tissues like bone, dentin and mineralized cartilage are difficult to prepare for ultrastructural analysis. In general, the higher the level of mineralization is, the more difficult it is to obtain ultrathin sections of these tissue. Tissues with a low level of mineral, e.g.
Everts, V., Hoeben, K.A.
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Electronic detectors for electron microscopy

Quarterly Reviews of Biophysics, 2011
AbstractElectron microscopy (EM) is an important tool for high-resolution structure determination in applications ranging from condensed matter to biology. Electronic detectors are now used in most applications in EM as they offer convenience and immediate feedback that is not possible with film or image plates.
Greg McMullan, A.R. Faruqi
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Electronic detectors for electron microscopy

Current Opinion in Structural Biology, 2007
Due to the increasing popularity of electron cryo-microscopy (cryoEM) in the structural analysis of large biological molecules and macro-molecular complexes and the need for simple, rapid and efficient readout, there is a persuasive need for improved detectors.
Richard Henderson, A.R. Faruqi
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Electron microscopy

2001
Abstract Despite the recent resurgence in the use of light microscopy (LM) due to the popularity of the confocal microscope coupled with the wide availability of image processing techniques (see Chapters 1 and 2), the unparalleled resolution offered by the electron microscope will maintain its importance as a basic tool in cell biology ...
Hawes, Chris   +1 more
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A Revolution in Electron Microscopy

Angewandte Chemie International Edition, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
John Meurig Thomas   +2 more
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Electron Microscopy Techniques

2014
This chapter introduces the basic concepts of electron microscopy, which comprises an extensive toolbox for characterizing the size, three-dimensional shape, composition, and crystal structure of nanoparticles, nanoparticle superstructures and nanostructured materials.
Heiner Friedrich, Marijn A. van Huis
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[21] Electron microscopy of chaperonins

1998
Publisher Summary The chapter presents a study related to electron microscopy of chaperonins. The chapter discusses several electron microscopy (EM) and image-processing methods that are useful for the study of chaperonin and the different kinds of information that they provide.
Chen, S., Roseman, A. M., Saibil, H. R.
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Correlated Light Microscopy and Electron Microscopy

2012
Understanding where, when, and how biomolecules (inter)act is crucial to uncover fundamental mechanisms in cell biology. Recent developments in fluorescence light microscopy (FLM) allow protein imaging in living cells and at the near molecular level. However, fluorescence microscopy only reveals selected biomolecules or organelles but not the (ultra ...
Ben N G Giepmans   +4 more
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Fixation for Electron Microscopy [PDF]

open access: possibleNature, 1963
IT is a common practice to use buffers for making up fixing solutions for study of biological materials by electron microscopy, and such buffered fixatives are considered advantageous. This belief seems to have resulted from researches in days when the development of preparative techniques was in its infancy; and embedding media, like epoxy resins and ...
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