Results 131 to 140 of about 5,113,203 (370)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
Nature Methods, 2017 S. Zheng +5 more
semanticscholar +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Photoswitchable single-walled carbon nanotubes for super-resolution microscopy in the near-infrared [PDF]
, 2019 Antoine G. Godin +6 more
openalex +1 more source
, 2006 The axial (z-) resolution of any fluorescence microscope using a single lens is limited by diffraction to >500nm. While a modest improvement by up to a factor of 2 may be achieved by mathematical deconvolution, a substantial improvement of the axial resolution requires a radical change of the physics of imaging Since the 1990s, two families of methods ...
Bewersdorf, Jörg +3 more
openaire +3 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
A Novel Method for Evaluation of Ore Minerals Based on Optical Microscopy and Image Analysis: Preliminary Results [PDF]
, 2022 Licia Santoro +4 more
openalex +1 more source
Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM)
Nature Methods, 2006 Michael J Rust, Mark Bates, X. Zhuang
semanticscholar +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source