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Microsomal metabolism of picene
Chemico-Biological Interactions, 1988Picene, a polycyclic aromatic hydrocarbon (PAH) of environmental relevance has recently been predicted to be carcinogenic, based on quantum mechanical calculation, although in several animal studies no carcinogenicity could be detected. In order to find out if the metabolism of this PAH can provide an explanation for its lack of carcinogenicity, picene
P. Petrovic +4 more
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2009
Proteomic profiling of subcellular compartments has many advantages over traditional proteomic approaches using whole cell lysates as it allows for detailed proteome analysis of a specific organelle and corresponding functional characteristics. The microsome is a critical, membranous compartment involved in the synthesis, sorting, and secretion of ...
Diana M, Wong, Khosrow, Adeli
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Proteomic profiling of subcellular compartments has many advantages over traditional proteomic approaches using whole cell lysates as it allows for detailed proteome analysis of a specific organelle and corresponding functional characteristics. The microsome is a critical, membranous compartment involved in the synthesis, sorting, and secretion of ...
Diana M, Wong, Khosrow, Adeli
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Microsomal hydroxylation of decane
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1969Abstract 1. 1. Aliphatic hydrocarbons (hexane, octane and decane) were oxidized in the microsomes from the livers of mouse, rat, rabbit, beef, pigeon and chick embryo. 2. 2. The oxidation of decane by mouse liver microsomes required NADPH and O 2 .
Kusunose Masamichi +2 more
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Science, 1969
Deoxyribonucleic acid has been isolated from the microsomes of mouse liver homogenates under conditions designed to prevent or greatly reduce mitochondrial and nuclear contamination. The DNA rapidly incorporates tritiated thymidine, and this, together with its reannealing characteristics after thermal denaturation, shows that it is not mitochondrial or
Doris P. Courington +3 more
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Deoxyribonucleic acid has been isolated from the microsomes of mouse liver homogenates under conditions designed to prevent or greatly reduce mitochondrial and nuclear contamination. The DNA rapidly incorporates tritiated thymidine, and this, together with its reannealing characteristics after thermal denaturation, shows that it is not mitochondrial or
Doris P. Courington +3 more
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Lipid Peroxidation of Rat‐Liver Microsomes [PDF]
European Journal of Biochemistry, 1973 Rat liver microsomes were peroxidized in vitro and chemical, physical and morphological changes in the membrane were related to the effects on certain membrane‐bound microsomal enzymes.With increasing peroxidation, microsomal phospholipids revealed decreasing concentrations of 20:4 and 22:6 fatty acids.
Anders Bergstrand +2 more
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[30] Microsomal lipid peroxidation
1978Publisher Summary This chapter discusses microsomal lipid peroxidation. Lipid peroxidation is a complex process known to occur in both plants and animals. It involves the formation and propagation of lipid radicals, the uptake of oxygen, a rearrangement of the double bonds in unsaturated lipids, and the eventual destruction of membrane lipids ...
Steven D. Aust, John A. Buege
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Virchows Archiv B Cell Pathology, 1976
Pieces of liver (in vitro ischemia) and isolated microsomes were subjected to incubation at 4 degrees C and 37 degrees C for various time intervals. The effects on microsomal protein, phospholipids, and cholesterol and on microsomal phosphatases and electron transport enzymes were followed as a functional of time and temperature.
Hans Glaumann, Louis Marzella
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Pieces of liver (in vitro ischemia) and isolated microsomes were subjected to incubation at 4 degrees C and 37 degrees C for various time intervals. The effects on microsomal protein, phospholipids, and cholesterol and on microsomal phosphatases and electron transport enzymes were followed as a functional of time and temperature.
Hans Glaumann, Louis Marzella
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1956
The spatial relationships of the myriad enzymes concerned in cell metabolism have assumed great significance in our efforts to understand the intergrated economy of the plant cell. During investigations into the intracellular distribution of enzymes, the biochemical activities of the mitochondria have been widely studied.
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The spatial relationships of the myriad enzymes concerned in cell metabolism have assumed great significance in our efforts to understand the intergrated economy of the plant cell. During investigations into the intracellular distribution of enzymes, the biochemical activities of the mitochondria have been widely studied.
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[6] Preparation of microsomes with calcium
1978Publisher Summary This chapter focuses on the preparation of microsomes with calcium. Isolation of the microsomal fraction of the hepatic cell employs a procedure of differential ultracentrifugation. This method is developed for mammalian liver tissue, but also employed to obtain microsomal fractions from a variety of tissues, such as lung, kidney ...
John B. Schenkman, Dominick L. Cinti
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Characteristics of b-type cytochromes in brain microsomes: Comparison with liver microsomes
Archives of Biochemistry and Biophysics, 1984Biochemical aspects of b-type cytochromes in swine cerebral microsomes were different from those of cytochrome b5 in liver microsomes, as well as the difference in absorption spectra. First, the kinetic constants, Km and Vmax, in rotenone-insensitive NADH-cytochrome c reductase activity were different from those of liver microsomes, and the activity of
Toshitsugu Yubisui +2 more
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