Results 311 to 320 of about 129,619 (377)
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Environmental Science and Technology, 2018
Tris(2-butoxyethyl) phosphate (TBOEP) and tris( n-butyl) phosphate (TNBP) are the most commonly used alkyl organophosphate esters (alkyl-OPEs), and they increasingly accumulate in organisms and create potential health hazards.
Rui Hou +4 more
semanticscholar +1 more source
Tris(2-butoxyethyl) phosphate (TBOEP) and tris( n-butyl) phosphate (TNBP) are the most commonly used alkyl organophosphate esters (alkyl-OPEs), and they increasingly accumulate in organisms and create potential health hazards.
Rui Hou +4 more
semanticscholar +1 more source
Proteomics, 2016
The purpose of the present study was to examine simultaneously the absolute protein amounts of 152 membrane and membrane‐associated proteins, including 30 metabolizing enzymes and 107 transporters, in pooled microsomal fractions of human liver, kidney ...
Kenji Nakamura +7 more
semanticscholar +1 more source
The purpose of the present study was to examine simultaneously the absolute protein amounts of 152 membrane and membrane‐associated proteins, including 30 metabolizing enzymes and 107 transporters, in pooled microsomal fractions of human liver, kidney ...
Kenji Nakamura +7 more
semanticscholar +1 more source
Interrogating Circulating Microsomes and Exosomes Using Metal Nanoparticles.
Small, 2016A chip-based approach for electrochemical characterization and detection of microsomes and exosomes based on direct electro-oxidation of metal nanoparticles (MNPs) that specifically recognize surface markers of these vesicles is reported.
Yi-Ge Zhou +9 more
semanticscholar +1 more source
In Vitro Drug Metabolism Using Liver Microsomes
Current Protocols in Pharmacology, 2016Knowledge of the metabolic stability of newly discovered drug candidates eliminated by metabolism is essential for predicting the pharmacokinetic (PK) parameters that underpin dosing and dosage frequency.
K. Knights +3 more
semanticscholar +1 more source
Microsomal metabolism of fluoroanilines
Xenobiotica, 19891. The microsomal, cytochrome P-450-dependent metabolism of fluoroanilines was studied using 19F-n.m.r. and also by a chemical assay for the hydroxy derivatives. 2. 2-Fluoro- and 3-fluoroaniline were preferentially hydroxylated at the para-position. 3. 4-Fluoroaniline was both p- and o-hydroxylated to a significant extent. 4.
Rietjens, I.M.C.M., Vervoort, J.
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Experientia, 1978
Studies which indicate the fusion of rat liver microsomal vesicles show that the rate of fusion of microsomal vesicles, as revealed by electron microscopic examinations, is dependent on the fusion temperature and the amount of detergent present in the microsomal suspension.
H. U. Schulze, Liliane Pop
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Studies which indicate the fusion of rat liver microsomal vesicles show that the rate of fusion of microsomal vesicles, as revealed by electron microscopic examinations, is dependent on the fusion temperature and the amount of detergent present in the microsomal suspension.
H. U. Schulze, Liliane Pop
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Effect of thiourea on microsomal oxidation alcohols and associated microsomal functions [PDF]
Biochemistry, 1979 Thiourea and diethylthiourea, two compounds which react with hydroxyl radicals, inhibited NADPH-dependent microsomal oxidation of ethanol and 1-butanol. Inhibition by both compounds was more effective in the presence of the catalase inhibitor, azide.
Elisa Dicker +3 more
openaire +2 more sources
Chemical Research in Toxicology, 2013
Polybrominated diphenyl ethers (PBDEs) were widely used flame retardants that have become persistent environmental pollutants. In the present study, we investigated the in vitro oxidative metabolism of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47), a major
C. Erratico, A. Szeitz, S. Bandiera
semanticscholar +1 more source
Polybrominated diphenyl ethers (PBDEs) were widely used flame retardants that have become persistent environmental pollutants. In the present study, we investigated the in vitro oxidative metabolism of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47), a major
C. Erratico, A. Szeitz, S. Bandiera
semanticscholar +1 more source
Xenobiotica; the fate of foreign compounds in biological systems, 2013
1. Hydrolytic metabolism of methyl-, ethyl-, propyl-, butyl-, heptyl- and dodecylparaben by various tissue microsomes and plasma of rats, as well as human liver and small-intestinal microsomes, was investigated and the structure–metabolic activity ...
H. Ozaki +7 more
semanticscholar +1 more source
1. Hydrolytic metabolism of methyl-, ethyl-, propyl-, butyl-, heptyl- and dodecylparaben by various tissue microsomes and plasma of rats, as well as human liver and small-intestinal microsomes, was investigated and the structure–metabolic activity ...
H. Ozaki +7 more
semanticscholar +1 more source
Effects of calmodulin antagonists on radiation-induced lipid peroxidation in microsomes.
International Journal of Radiation Biology, 1990Rat liver microsomes were irradiated with gamma-rays at a dose rate of 1.31 Gys-1. The extent of lipid peroxidation, measured in terms of malondialdehyde (MDA) formed, increased with radiation dose.
R. Varshney, R. Kale
semanticscholar +1 more source