Results 331 to 340 of about 129,619 (377)
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Environmental Toxicology and Chemistry, 2009
Metabolism plays an important role in bioaccumulation of xenobiotics in fish. The applicability of trout liver microsomes and S9 fraction in bioaccumulation assessment of xenobiotics in fish was investigated in the present study.
X. Han +4 more
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Metabolism plays an important role in bioaccumulation of xenobiotics in fish. The applicability of trout liver microsomes and S9 fraction in bioaccumulation assessment of xenobiotics in fish was investigated in the present study.
X. Han +4 more
semanticscholar +1 more source
[30] Microsomal lipid peroxidation
1978Publisher Summary This chapter discusses microsomal lipid peroxidation. Lipid peroxidation is a complex process known to occur in both plants and animals. It involves the formation and propagation of lipid radicals, the uptake of oxygen, a rearrangement of the double bonds in unsaturated lipids, and the eventual destruction of membrane lipids ...
Steven D. Aust, John A. Buege
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Acta Pharmacologica et Toxicologica, 2009
Microsomes were prepared from the liver, kidney and lung of phenobarbital or 20-methylcholanthrene treated and control rats with the conventional ultracentrifugation and calcium aggregation methods.
A. Aitio, H. Vainio
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Microsomes were prepared from the liver, kidney and lung of phenobarbital or 20-methylcholanthrene treated and control rats with the conventional ultracentrifugation and calcium aggregation methods.
A. Aitio, H. Vainio
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Virchows Archiv B Cell Pathology, 1976
Pieces of liver (in vitro ischemia) and isolated microsomes were subjected to incubation at 4 degrees C and 37 degrees C for various time intervals. The effects on microsomal protein, phospholipids, and cholesterol and on microsomal phosphatases and electron transport enzymes were followed as a functional of time and temperature.
Hans Glaumann, Louis Marzella
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Pieces of liver (in vitro ischemia) and isolated microsomes were subjected to incubation at 4 degrees C and 37 degrees C for various time intervals. The effects on microsomal protein, phospholipids, and cholesterol and on microsomal phosphatases and electron transport enzymes were followed as a functional of time and temperature.
Hans Glaumann, Louis Marzella
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Oxidized redox state of glutathione in the endoplasmic reticulum.
Science, 1992The redox state of the endoplasmic reticulum (ER) was measured with the peptide N-Acetyl-Asn-Tyr-Thr-Cys-NH2. The peptide diffused across cellular membranes; some became glycosylated and thus trapped within the secretory pathway, and its cysteine residue
C. Hwang, A. Sinskey, H. Lodish
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Carcinogenesis, 1992
An acetyltransferase-overexpressing strain of Salmonella typhimurium (NM2009) has been used to investigate roles of human liver microsomal cytochrome P450 (P450) enzymes in the activation of carcinogenic nitrosamine derivatives, including N ...
H. Yamazaki +4 more
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An acetyltransferase-overexpressing strain of Salmonella typhimurium (NM2009) has been used to investigate roles of human liver microsomal cytochrome P450 (P450) enzymes in the activation of carcinogenic nitrosamine derivatives, including N ...
H. Yamazaki +4 more
semanticscholar +1 more source
1956
The spatial relationships of the myriad enzymes concerned in cell metabolism have assumed great significance in our efforts to understand the intergrated economy of the plant cell. During investigations into the intracellular distribution of enzymes, the biochemical activities of the mitochondria have been widely studied.
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The spatial relationships of the myriad enzymes concerned in cell metabolism have assumed great significance in our efforts to understand the intergrated economy of the plant cell. During investigations into the intracellular distribution of enzymes, the biochemical activities of the mitochondria have been widely studied.
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[6] Preparation of microsomes with calcium
1978Publisher Summary This chapter focuses on the preparation of microsomes with calcium. Isolation of the microsomal fraction of the hepatic cell employs a procedure of differential ultracentrifugation. This method is developed for mammalian liver tissue, but also employed to obtain microsomal fractions from a variety of tissues, such as lung, kidney ...
John B. Schenkman, Dominick L. Cinti
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Drug Metabolism And Disposition, 2004
Oxycodone undergoes N-demethylation to noroxycodone and O-demethylation to oxymorphone. The cytochrome P450 (P450) isoforms capable of mediating the oxidation of oxycodone to oxymorphone and noroxycodone were identified using a panel of recombinant human
Bojan Lalovic +4 more
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Oxycodone undergoes N-demethylation to noroxycodone and O-demethylation to oxymorphone. The cytochrome P450 (P450) isoforms capable of mediating the oxidation of oxycodone to oxymorphone and noroxycodone were identified using a panel of recombinant human
Bojan Lalovic +4 more
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Characteristics of b-type cytochromes in brain microsomes: Comparison with liver microsomes
Archives of Biochemistry and Biophysics, 1984Biochemical aspects of b-type cytochromes in swine cerebral microsomes were different from those of cytochrome b5 in liver microsomes, as well as the difference in absorption spectra. First, the kinetic constants, Km and Vmax, in rotenone-insensitive NADH-cytochrome c reductase activity were different from those of liver microsomes, and the activity of
Toshitsugu Yubisui +2 more
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