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Microspheres are multiparticulate drug delivery systems which are prepared to obtain prolonged the controlled drug delivery to improve bioavailability, stability and to target the drug to specific site at a predetermined rate. They are made from polymeric waxy or other protective materials such as natural, semi synthetic and synthetic polymers ...
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Development and Evaluation of Controlled-Release Diclofenac Microspheres and Tabletted Microspheres
Journal of Microencapsulation, 1994Diclofenac wax microspheres were prepared using the congealable dispersephase encapsulation method. Emulsifiers, glyceryl monostearate (GMS) and stearic acid, were added to improve the efficiency of emulsification. Microspheres containing either of the emulsifiers or both showed a high drug content (80-90%) and the particle size distribution was log ...
V D Vilivalam, C M Adeyeye
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Journal of Microencapsulation, 2001
This study is an attempt to prepare microspheres loaded with two antihypertensive drugs viz., nifedipine (NFD) and verapamil hydrochloride (VRP) using cellulose-based polymers viz., ethyl cellulose (EC) and cellulose acetate (CA). Emulsification and solvent evaporation methods were optimized using ethyl acetate as a dispersing solvent.
Kumaresh Soppimath+2 more
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This study is an attempt to prepare microspheres loaded with two antihypertensive drugs viz., nifedipine (NFD) and verapamil hydrochloride (VRP) using cellulose-based polymers viz., ethyl cellulose (EC) and cellulose acetate (CA). Emulsification and solvent evaporation methods were optimized using ethyl acetate as a dispersing solvent.
Kumaresh Soppimath+2 more
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Sterility assurance of microspheres
Journal of Controlled Release, 1999The International Conference on Harmonization (ICH) provides a forum for constructive dialogues between regulatory authorities and the pharmaceutical industry on the real and perceived differences in the technical requirements for product registration in the EU, US and Japan. Achievement obtained so far is beyond expectation, having strong impacts both
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Colon‐Targeted Adhesive Hydrogel Microsphere for Regulation of Gut Immunity and Flora
Advanced Science, 2021Hua Liu, Jie Zhong, Lianfu Deng
exaly
Super‐resolution optical microscopy based on scannable cantilever‐combined microsphere
Microscopy Research and Technique, 2015Dongxian Zhang
exaly