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The stability of proteinoid microspheres

Biosystems, 1994
Proteinoid microspheres are stable hollow spheres of diameter of the order of 5 microns. Their stability is discussed in terms of macroscopic energies. It is shown that bulk and surface energy contributions alone cannot lead to stable microspheres. If electrostatic energy, due to transmembrane voltage, is taken into account, stable hollow spheres are ...
Müller-Herold U, Nickel G
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Development and Evaluation of Controlled-Release Diclofenac Microspheres and Tabletted Microspheres

Journal of Microencapsulation, 1994
Diclofenac wax microspheres were prepared using the congealable dispersephase encapsulation method. Emulsifiers, glyceryl monostearate (GMS) and stearic acid, were added to improve the efficiency of emulsification. Microspheres containing either of the emulsifiers or both showed a high drug content (80-90%) and the particle size distribution was log ...
V D, Vilivalam, C M, Adeyeye
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Metabolic microspheres

Naturwissenschaften, 1980
A systematic review of catalytic activities in thermal proteinoids and microspheres aggregated therefrom yields some new inferences on the origins and evolution of metabolism. Experiments suggest that, instead of being inert, protocells were already biochemically and cytophysically competent. The emergence and refinement of metabolism ab initio is thus
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Multilayered Polymer Microspheres by Thermal Imprinting during Microsphere Growth

Journal of the American Chemical Society, 2005
Modulation of the polymerization temperature in precipitation polymerizations was used to form onion-type polymer microspheres consisting of multiple nested layers. Specifically, the copolymerization of chloromethylstyrene and divinylbenzene-55 in acetonitrile, at temperatures ramping between 65 and 75 degrees C, led to monodisperse, cross-linked ...
Ryu, Takekoh   +3 more
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Encapsulation of antihypertensive drugs in cellulose-based matrix microspheres: characterization and release kinetics of microspheres and tableted microspheres

Journal of Microencapsulation, 2001
This study is an attempt to prepare microspheres loaded with two antihypertensive drugs viz., nifedipine (NFD) and verapamil hydrochloride (VRP) using cellulose-based polymers viz., ethyl cellulose (EC) and cellulose acetate (CA). Emulsification and solvent evaporation methods were optimized using ethyl acetate as a dispersing solvent.
K S, Soppimath   +2 more
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Synthesis of CuInS2 Microspheres using In2S3 Microspheres as Templates

Australian Journal of Chemistry, 2009
CuInS2 microspheres have been prepared via a solvothermal route employing synthetic In2S3 microspheres as templates. X-ray diffraction analysis reveals that CuInS2 crystals assembled from In2S3 microsphere building blocks are tetragonal phase. Field emission scanning electron microscopy and transmission electron microscopy images show that the prepared
Ming Ge   +4 more
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Microsphere: A Review

Research Journal of Topical and Cosmetic Sciences, 2016
Microspheres are characteristically free flowing powders consisting of proteins or synthetic polymers having a particle size ranging from 1-1000 μm. The range of Techniques for the preparation of microspheres offers a variety of opportunities to control aspects of drug administration and enhance the therapeutic efficacy of a given drug.
Deepak S. Kshirsagar, R. B. Saudagar
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Sterility assurance of microspheres

Journal of Controlled Release, 1999
The International Conference on Harmonization (ICH) provides a forum for constructive dialogues between regulatory authorities and the pharmaceutical industry on the real and perceived differences in the technical requirements for product registration in the EU, US and Japan. Achievement obtained so far is beyond expectation, having strong impacts both
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From Zn microspheres to hollow ZnO microspheres: A simple route to the growth of large scale metallic Zn microspheres and hollow ZnO microspheres

Physica E: Low-dimensional Systems and Nanostructures, 2006
Abstract Large scale metallic Zn microspheres and hollow ZnO microspheres are synthesized by thermal evaporation and vapor transport by heating a ZnO/graphite mixture at 1000 °C. Firstly, metallic Zn microspheres are fabricated with diameters in the range of 1–10 μm.
Aurangzeb Khan   +2 more
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PLGA Microspheres Encapsulating siRNA

2014
The therapeutic use of small interfering RNA (siRNA) represents a new and powerful approach to suppress the expression of pathologically genes. However, biopharmaceutical drawbacks, such as short half-life, poor cellular uptake, and unspecific distribution into the body, hamper the development of siRNA-based therapeutics.
DE ROSA, GIUSEPPE, SALZANO, GIUSEPPINA
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