Results 91 to 100 of about 27,773 (162)

Analysis of quality of life and outcomes of vestibular schwannoma patients after resection and radiosurgery in an interdisciplinary treatment concept

open access: yesScientific Reports
Quality of life (QoL) is a crucial factor which has to be taken into account in the treatment of vestibular schwannomas. This study compared microsurgical and radiosurgical treatments, focusing on three.
Alexander Romagna   +6 more
doaj   +1 more source

Nanorobotic platforms for targeted drug delivery: Materials engineering, functional dynamics, and biomedical translation

open access: yesClinical and Translational Discovery, Volume 6, Issue 3, June 2026.
Graphical representation of nanorobotic platforms for targeted drug delivery. Abstract Background Nanorobotic systems represent an emerging and disruptive paradigm in nanomedicine for precision drug delivery, controlled therapeutic release, and minimally invasive biomedical interventions.
Mohd Shoab Ali   +5 more
wiley   +1 more source

Cancer IDO1‐Mediated Tryptophan–Kynurenine Metabolic Reprogramming to Drive Skeletal Muscle Atrophy and Cachexia Acceleration

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Cancer cachexia is a debilitating syndrome characterized by severe skeletal muscle wasting, which significantly impairs patient quality of life and survival. Indoleamine 2,3‐dioxygenase 1 (IDO1), a key enzyme in tryptophan (Trp) metabolism, is often upregulated in cancers, but its specific role in driving lung cancer–associated ...
Leng Han   +12 more
wiley   +1 more source

MyoRep: A Novel Reporter System to Detect Early Muscle Atrophy In Vitro and In Vivo

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Muscle atrophy occurs during physiological (i.e., fasting) and pathological conditions (i.e., cancer) and anticipates death. Since not all patients will undergo muscle wasting, it would be highly useful to identify them soon to intervene early.
Andrea D. Re Cecconi   +11 more
wiley   +1 more source

RIPK3 Inhibition Mitigates Denervated Muscle Atrophy via NOX4‐Mediated Mitochondrial Restoration and Inflammation Suppression

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Peripheral nerve injury‐induced muscle atrophy shares core pathophysiological features with systemic wasting disorders including cachexia and sarcopenia, yet early molecular triggers remain undefined. This study investigates the pathogenic role of receptor‐interacting protein kinase 3 (RIPK3) in denervation atrophy.
Yuntian Shen   +6 more
wiley   +1 more source

Upper Airway Obstruction due to Kaposi Sarcoma—Presenting Sign of HIV: Case Report and Review

open access: yesThe Laryngoscope, Volume 136, Issue 6, Page 2631-2637, June 2026.
This study presents a case of undiagnosed HIV presenting with Kaposi sarcoma (KS) of the head and neck with acute upper airway obstruction (UAO) and provides an updated scoping literature review to examine the patient characteristics, lesion characteristics, interventions, and outcomes of KS cases with UAO from the pharynx, larynx, and/or trachea.
Zachary A. Wykoff   +3 more
wiley   +1 more source

Medicare Utilization and Reimbursement Trends for Free Flaps in Otolaryngology, Plastic Surgery, and Maxillofacial Surgery

open access: yesOtolaryngology–Head and Neck Surgery, Volume 174, Issue 6, Page 1642-1646, June 2026.
Abstract Free flap procedures are important components of reconstructive surgery in otolaryngology, plastic surgery, and maxillofacial surgery. This research investigates trends in utilization, charges, and Medicare reimbursements for free flap procedures performed across these specialties.
Kyle Polen   +4 more
wiley   +1 more source

Microrobots: Two Decades of Progress

open access: yesSmartBot, Volume 2, Issue 2, June 2026.
Microrobots are governed by counterintuitive viscous‐dominated microscale physics, making traditional large‐scale driving principles unapplicable and restricting their reliable in‐body locomotion implementation. Multiple propulsion schemes and advanced microfabrication techniques have been developed to bypass such physical limitations and enrich ...
Bradley J. Nelson
wiley   +1 more source

In Vitro and In Vivo Evaluation of Decellularized Porcine Femoral Aorta Reinforced With Electrospun Coarse Polycaprolactone Fibers for Vascular Graft Application

open access: yesArtificial Organs, Volume 50, Issue 6, Page 813-824, June 2026.
This study aims to develop a hybrid small‐diameter vascular graft by combining electrospun PCL with decellularized porcine femoral aorta (PECM). The graft showed complete decellularization, strong mechanical integrity, and no layer delamination.
Hyun‐Yong Lee   +8 more
wiley   +1 more source

Temporal trends in colorectal resections for benign colorectal neoplasia: A retrospective cohort study of the ACS‐NSQIP 2016–2022

open access: yesColorectal Disease, Volume 28, Issue 6, June 2026.
Abstract Background Colorectal cancer (CRC) screening programmes in North America have effectively reduced CRC incidence. Among the nearly six million colonoscopies performed annually in the United States, 4%–11% detect large benign colorectal neoplasms, many of which can be removed endoscopically, minimizing the need for surgery. Endoscopic removal is
Sahil Sharma   +9 more
wiley   +1 more source

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