Results 51 to 60 of about 86,338 (329)

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla   +16 more
wiley   +1 more source

Concurrent Segmentation and Localization for Tracking of Surgical Instruments

open access: yes, 2017
Real-time instrument tracking is a crucial requirement for various computer-assisted interventions. In order to overcome problems such as specular reflections and motion blur, we propose a novel method that takes advantage of the interdependency between ...
D Bouget   +10 more
core   +1 more source

A modified sentinel node and occult lesion localization (SNOLL) technique in non-palpable breast cancer. A pilot study [PDF]

open access: yes, 2015
Background: The spread of mammographic screening programs has allowed an increasing amount of early breast cancer diagnosis. A modern approach to non-palpable breast lesions requires an accurate intraoperative localization, in order to achieve a ...
Anibaldi, Paolo   +8 more
core   +2 more sources

Modulus‐Switchable Miniature Robots for Biomedical Applications: A Review

open access: yesAdvanced Robotics Research, EarlyView.
Materials, robot designs, proof‐of‐concept functions, and biomedical applications of modulus‐switchable miniature robots. Miniature soft robots have shown great potential in biomedical applications due to their excellent controllability and suitable mechanical properties in biological environments.
Chunyun Wei, Yibin Wang, Jiangfan Yu
wiley   +1 more source

Survey of Microsurgery Training Availability in US Urology Residency Programs

open access: yesThe World Journal of Men's Health, 2021
Purpose: The Accreditation Council of Graduate Medical Education (ACGME) establishes surgical minimum numbers of cases for urologic training. Currently there is not a requirement for microsurgery, likely from a belief that programs do not offer ...
Thomas A. Masterson   +5 more
doaj   +1 more source

ILM removal in vitreomacular interface disorders: for or against?

open access: yesОфтальмохирургия, 2021
Purpose. To provide data on efficacy and safety of internal limiting membrane (ILM) removal in various pathologies of the vitreomacular interface. Material and methods. To perform the review, literature sources were searched through the PubMed and Scopus
S. V. Kolesnik   +4 more
doaj   +1 more source

Hard‐Magnetic Soft Millirobots in Underactuated Systems

open access: yesAdvanced Robotics Research, EarlyView.
This review provides a comprehensive overview of hard‐magnetic soft millirobots in underactuated systems. It examines key advances in structural design, physics‐informed modeling, and control strategies, while highlighting the interplay among these domains.
Qiong Wang   +4 more
wiley   +1 more source

Does an Analysis of the Pulsatile Secretion Pattern of Adrenocorticotropin and Cortisol Predict the Result of Transsphenoidal Surgery in Cushing’s Disease. [PDF]

open access: yes, 1993
The endocrinological, surgical, and histological findings of patients with ACTH-dependent Cushing's disease were correlated with the pulsatile secretion pattern of ACTH and cortisol and the outcome after transsphenoidal pituitary surgery.
Brabant, Georg   +5 more
core   +1 more source

Recent Advances in Robotic Systems for Robot‐Assisted Transoral Surgical Procedures: A Systematic Review

open access: yesAdvanced Robotics Research, EarlyView.
This review systematically examines robotic systems for robot‐assisted transoral surgical procedures, classifying them based on transoral access depth, and evaluates their fundamental design principles, mechanical innovations, algorithmic advancements, and clinical implementation status.
Yuhao Shi   +5 more
wiley   +1 more source

Postoperative care in finger replantation. Our case-load and review of the literature [PDF]

open access: yes, 2015
OBJECTIVE: Technical success of a finger replantation depends on several factors such as surgical procedure, type of injury, number of segments amputated, amputation level and individual patient factors.
Chen, Hc   +6 more
core  

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