Targeting the MDK/c-Myc complex to overcome temozolomide resistance in glioma. [PDF]
Clin Transl MedACT001 disrupts the MDK/c‐Myc complex, enhancing c‐Myc ubiquitination and overcoming temozolomide resistance in glioma. Combining ACT001 with temozolomide synergistically inhibits tumour growth and progression, offering a promising therapeutic strategy for glioma patients, particularly those with high MDK expression.
Xi X +7 more
europepmc +2 more sources
Frontiers in Earth Science, 2021 The giant Gejiu Sn–Cu polymetallic ore deposit is one of the largest Sn producers in the world, and is related in time and space to highly evolved S type granitic intrusion. The mineralization processes can be divided into four stages: (I) skarnization; (
Yongqing Chen +3 more
doaj +1 more source
Fluids in the Siilinjärvi carbonatite complex, eastern Finland: Fluid inclusion evidence for the formation conditions of zircon and apatite [PDF]
Bulletin of the Geological Society of Finland, 1995 In the studied zircon and apatite crystals, data recorded two different compositional types of fluid inclusions: Type 1 H2O-CO2 low salinity inclusions (XCO2 = 0.42 to 0.87; XNaCl = 0.001 to 0.005) with bulk densities of 0.73 to 0.87 g/cm3, and Type 2 ...
M. Poutiainen
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Fluid inclusions in cavity quartz crystals in rapakivi from Luumäki, southeastern Finland [PDF]
Bulletin of the Geological Society of Finland, 1991 Fluid inclusions in selected cavity quartz crystals in rapakivi granite from Luumäki, southeastern Finland, were studied by microthermometric methods.
M. Poutiainen
doaj +1 more source
Multi-proxy speleothem-based reconstruction of mid-MIS 3 climate in South Africa [PDF]
Climate of the Past, 2023 The southern coast of South Africa displays a highly dynamical climate as it is at the convergence of the Atlantic and Indian oceans, and it is located near the subtropical/temperate zone boundary with seasonal influence of easterlies and westerlies. The
J. Maccali +15 more
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Geochemistry and Fuid-Inclusion Microthermometry of the Farsesh Barite Deposit, Iran [PDF]
Geologos, 2014 Abstract The Permian carbonate-hosted Farsesh barite deposit is located southeast of the City of Aligudarz in the province of Lorestan, Iran. Structurally, this deposit lies in the Zagros metallogenic belt and the Sanandaj-Sirjan Zone.
Zarasvandi, Alireza +4 more
openaire +3 more sources
Quartz-amethyst hosted hydrocarbon-bearing fluid inclusions from the green ridge breccia in the snoqualmie granite, North Cascades,WA, USA [PDF]
, 2017 We wish to acknowledge the constructive criticisms made by the three anonymous reviewers.Their suggestions and comments greatly improved the first version of the manuscript.Peer reviewedPublisher ...
Baba, Mas’Ud +7 more
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Hydrocarbon Charge History of the Upper Paleozoic, Ordos Basin as Revealed by Fluid Inclusions
Frontiers in Physics, 2022 The petrographic characteristics of fluid inclusions of the main gas-bearing intervals of the Upper Paleozoic in the Ordos Basin are analyzed by means of plane-polarized light, fluorescence microscopy, and microthermometry. With the burial history of the
Qing Cao +4 more
doaj +1 more source
Indicators of hot fluid migration in sedimentary basins: evidence from the UK Atlantic Margin [PDF]
, 2003 Microthermometric, petrographic and isotopic methods have been used to detect evidence for hot fluid flow in Mesozoic and Tertiary sediments from the NW UK continental margin, West of Shetland. New data presented here show that temperatures are hotter by
Boyce, A.J. +4 more
core +1 more source
Dye-Doped ZnO Microcapsules for High Throughput and Sensitive Optofluidic Micro-Thermometry
Micromachines, 2020 The main objective of this work is to show the proof of concept of a new optofluidic method for high throughput fluorescence-based thermometry, which enables the measure of temperature inside optofluidic microsystems at the millisecond (ms) time scale ...
Najla Ghifari +5 more
doaj +1 more source