Results 121 to 130 of about 148,622 (241)

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

Environmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz, Melanie Blanc‐Legendre, Maximilian Rinderknecht, Laura Behnstedt, Sara Coordes, Luisa Reger, Sacha Sire, Xavier Cousin, Thomas Braunbeck, Lisa Baumann   +9 more
wiley   +1 more source

Micromorphological features of brown rotted wood revealed by broad argon ion beam milling. [PDF]

Sci Rep
Tsukida R, Hatano T, Kojima Y, Nakaba S, Horikawa Y, Funada R, Goodell B, Yoshida M.   +7 more
europepmc   +1 more source

Building a Microtome

The American Biology Teacher, 1943
Delbert Hawkins, Tom Sergeant
openaire   +2 more sources

Engineered Exosome‐Based Senolytic Therapy Alleviates Stroke by Targeting p21+CD86+ Microglia

Exploration, EarlyView.
We identified a harmful immune cell type, p21+CD86+ microglia, driving post‐stroke inflammation and developed a targeted exosome‐based therapy (Que@micro‐Exo) to eliminate these cells. This innovative treatment reduced inflammation, alleviated brain damage, and improved recovery in stroke models, offering a promising strategy for stroke and other ...
Jialei Yang, Shipo Wu, Miao He
wiley   +1 more source

CELS-3D-Cutting edge light source for exciting fluorescence in microtome-based 3D microscopy and targeted correlative microscopy. [PDF]

J Anat
Denyshchenko V, Evans C, O'Neill T, Krstev J, Filipczak E, O'Toole S, Lobaskin V, Scholz D.   +7 more
europepmc   +1 more source

High‐Precision, Low‐Threshold Neuromodulation With Ultraflexible Electrode Arrays for Brain‐to‐Brain Interfaces

Exploration, EarlyView.
Traditional neuromodulation using rigid electrodes has been limited by low precision, large stimulating currents, and the risk of tissue damage. In this work, we developed a biocompatible flexible electrode array that allows for both neural recording of spike firings and high‐precision, low‐threshold stimulation for neuromodulation.
Yifei Ye, Ye Tian, Haifeng Liu, Jiaxuan Liu, Cunkai Zhou, Chengjian Xu, Ting Zhou, Yanyan Nie, Yu Wu, Lunming Qin, Zhitao Zhou, Xiaoling Wei, Jianlong Zhao, Zhenyu Wang, Meng Li, Tiger H. Tao, Liuyang Sun   +16 more
wiley   +1 more source

Integrated 3D imaging of FFPE lung tissue combining microCT, light and electron microscopy allows for contextualized ultrastructural and histological analysis. [PDF]

Sci Rep
Reiser J, Albers J, Svetlove A, Mertiny M, Kommoss FKF, Schwab C, Schneemann A, Tromba G, Wacker I, Curticean RE, Schroeder RR, Kauczor HU, Wielpütz MO, Dullin C, Wagner WL.   +14 more
europepmc   +1 more source

Glial Versus Neuronal Na+/K+‐ATPase in Activity‐Evoked K+ Clearance and Their Sensitivity to Elevated Extracellular K+

Glia, EarlyView.
The glial Na+ pump regulates [K+]o during neuronal activity, and the neuronal version restores [K+]o to baseline. Spreading depression‐related rise of K+ does not cause SD propagation via suppression of Na+/K+‐ATPase or glutamate transport. ABSTRACT Neuronal activity in the central nervous system is associated with a [K+]o transient that is swiftly ...
Brian Skriver Nielsen, Brian Roland Larsen, Afnan Bilal Ghazal, Adriana Katz, K. C. Brennan, Steven J. D. Karlish, Nanna MacAulay   +6 more
wiley   +1 more source

CRISPR/Cas9‐mediated genome editing reveals seven testis‐enriched transmembrane glycoproteins dispensable for male fertility in mice

Andrology, EarlyView., 2023
Abstract Background Mammalian fertilization is mediated by multiple sperm acrosomal proteins, many of which are testis‐enriched transmembrane glycoproteins expressed during spermiogenesis (e.g., Izumo sperm‐egg fusion 1, Sperm acrosome associated 6, and Transmembrane protein 95).
Yo Ogawa, Yonggang Lu, Daiji Kiyozumi, Hsin‐Yi Chang, Masahito Ikawa   +4 more
wiley   +1 more source

Variation in Vessel Element Diameters and Densities Across Habitats at the Community and Species Levels in Southeast Florida. [PDF]

Biology (Basel)
Rogers GK.
europepmc   +1 more source