STING deficiency promotes motor recovery in mice following brachial plexus root avulsion
Animal Models and Experimental Medicine, EarlyView.STING deficiency can increase the body weight, promote motor recovery, decrease MN death, inhibit pyroptosis and neuroinflammation, increase remyelination, and reduce the atrophy of the biceps brachii in mice with BPRA. Abstract Background Brachial plexus root avulsion (BPRA), a well‐known form of peripheral nerve injury, results in motor function loss
Yu Peng +4 more
wiley +1 more source
Improved Immunohistochemistry of Mouse Eye Sections Using Davidson's Fixative and Melanin Bleaching. [PDF]
Bio ProtocLongakit AN +3 more
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Characterization of inflammatory pseudotumors in a large animal model of liver cancer
Animal Models and Experimental Medicine, EarlyView.CT images in arterial and portal venous phases of liver lesions in Oncopig. Abstract Background The development of relevant and robust large animal models of hepatocellular carcinoma is needed to test new therapeutic strategies for this disease. Transgenic approaches hold promise in addressing this complex problem. One such model, the Oncopig, has been
Erik N. K. Cressman +4 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.An 18‐month HFD successfully established a translational Macaca fascicularis model replicating key metabolic disorders (MASH, diabetes, cardiac hypertrophy). MASH was determined by liver biopsy histology, the presence steatosis, inflammatory infiltration, hepatocytic ballooning, and fibrosis were considered as MASH; diabetes was diagnosed according to ...
Hongyi Chen +12 more
wiley +1 more source
Generation of Agarose-Based FFPE Cancer Organoids for Morphology Preservation. [PDF]
Bio ProtocLee MR +5 more
europepmc +1 more source
AN ARRANGEMENT FOR USING THE BLADES OF SAFETY RAZORS IN THE MICROTOME
, 1911 Bill Bentley
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Establishment of a mouse model of TMAO‐induced cardiac injury and application of MICT intervention
Animal Models and Experimental Medicine, EarlyView.This study aims to explore the establishment of an animal model of cardiac injury induced by trimethylamine‐N‐oxide (TMAO), a metabolite secreted by gut microorganisms, and to investigate its application in moderate‐intensity continuous training (MICT) intervention.
Zhongping Xie +4 more
wiley +1 more source
Protocol for the Systematic Quantitative Ultrastructural Analysis of Mitochondria in Cardiac Tissue. [PDF]
Methods ProtocSchönmehl R +7 more
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Hydroxycarboxylic Acid Receptor 2 Mediates β‐hydroxybutyrate's Antiseizure Effect in Mice
Annals of Neurology, EarlyView.A Objective The ketogenic diet, a high‐fat, low‐carbohydrate regimen, is often used to treat drug‐resistant seizures and is being studied for Alzheimer's disease and other neuropsychiatric disorders. However, its mechanism of action remains unclear. β‐hydroxybutyrate, a primary circulating ketone body produced by the ketogenic diet, may mediate its ...
Soudabeh Naderi +10 more
wiley +1 more source
Numerical Investigations of the Seam Opening Behavior of Peelable Seal Seams as a Function of the Seal Seam Formation. [PDF]
Polymers (Basel)Götz M, Kayatz F, Hauptmann M.
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