Results 31 to 40 of about 92,130 (198)

Come together over me: Cells that form the dermatocranium and chondrocranium in mice

The Anatomical Record, EarlyView., 2023
Abstract Most bone develops either by intramembranous ossification where bone forms within a soft connective tissue, or by endochondral ossification by way of a cartilage anlagen or model. Bones of the skull can form endochondrally or intramembranously or represent a combination of the two types of ossification.
M. Kathleen Pitirri, Joan T. Richtsmeier, Mizuho Kawasaki, Abigail P. Coupe, Susan Motch Perrine, Kazuhiko Kawasaki   +5 more
wiley   +1 more source

Elucidating and Biomimicking the Coloration Mechanisms Responsible for the Vibrant Blue Hues of the Common Kingfisher

Advanced Optical Materials, EarlyView.
This study reveals why the back feathers of a common kingfisher show various non‐iridescent blueish structural colors by analyzing the internal structures of the feathers. It demonstrates how structural differences lead to the different optical interactions, thereby producing different colors.
Jihun Kang, Seunghwan Moon, Deok‐Jin Jeon, Seungmuk Ji, Eunok Lee, Jong‐Souk Yeo   +5 more
wiley   +1 more source

Thermo‐Optical Analysis of Surface‐ and Volume‐Additivated Polymer Powders for Near‐Infrared Laser Powder Bed Fusion

Advanced Photonics Research, EarlyView.
Precipitated PA11 powders for laser powder bed fusion are additivated with small amounts of carbon black nanoparticles on and in the particles. The position of the nanoparticles has a strong impact on dispersion, crystallization, and thermal oxidation.
Alexander Sommereyns, Jochen Schmidt, Cheechau Leong, Florentin Tischer, Michael Schmidt   +4 more
wiley   +1 more source

Activation of Glutamatergic Neurons in the Supramammillary Nucleus Promotes the Recovery of Consciousness under Sevoflurane Anesthesia

Advanced Science, EarlyView.
Selective lesioning of SuM glutamatergic neurons promoted the induction of and delayed emergence from sevoflurane anesthesia and increased sevoflurane sensitivity. Optogenetic stimulation of SuM glutamatergic neurons or the SuM‐MS projection promoted behavioral arousal and cortical activation under steady‐state sevoflurane anesthesia and reduced the ...
Jiayan Li, Yehui Wu, Yihan Wang, Yumin Wu, Rong Hu, Si Long, Wenqi Huang, Liming Nie, Zhongxing Wang   +8 more
wiley   +1 more source

Functional Polarization of Liver Macrophages by Glyco Gold Nanoparticles

Advanced Science, EarlyView.
Macrophages play a critical role in several pathophysiological diseases by being involved in the activation of adaptive and innate immune responses. The repolarization of macrophages using gold nanoparticles functionalized with glycans for a more selective targeting toward a restorative phenotype leads to an amelioration of the events.
Jennifer Fernandez Alarcon, Patricia Perez Schmidt, Nicolo Panini, Francesca Caruso, Martina B. Violatto, Naths Grazia Sukubo, Alberto Martinez‐Serra, Charlotte Blanche Ekalle‐Soppo, Annalisa Morelli, Giulia Yuri Moscatiello, Chiara Grasselli, Alessandro Corbelli, Fabio Fiordaliso, Joe Kelk, Laura Petrosilli, Giuseppe d'Orazio, Ruth Mateu Ferrando, Ariadna Verdaguer Ferrer, Cristina Fornaguera, Luigi Lay, Stefano Fumagalli, Sandro Recchia, Marco P. Monopoli, Laura Polito, Paolo Bigini, Giovanni Sitia   +25 more
wiley   +1 more source

Bioprinted Patient‐Derived Organoid Arrays Capture Intrinsic and Extrinsic Tumor Features for Advanced Personalized Medicine

Advanced Science, EarlyView.
An embedded bioprinting enabled‐arrayed patient‐derived organoids (Eba‐PDO) platform that replicates intrinsic and extrinsic tumor characteristics is introduced. Eba‐PDOs more accurately mimic tissue than standard PDOs (Std‐PDOs) due to maturation in the tumor microenvironment.
Jonghyeuk Han, Hye‐Jin Jeong, Jeonghan Choi, Hyeonseo Kim, Taejoon Kwon, Kyungjae Myung, Kyemyung Park, Jung In Park, Samuel Sánchez, Deok‐Beom Jung, Chang Sik Yu, In Ho Song, Jin‐Hyung Shim, Seung‐Jae Myung, Hyun‐Wook Kang, Tae‐Eun Park   +15 more
wiley   +1 more source

Pinoresinol Diglucoside Attenuates Nuclear Receptor Coactivator 4‐Mediated Ferritinophagy Associated with Cisplatin‐Induced Hearing Loss

Advanced Science, EarlyView.
Pinoresinol diglucoside, a bioactive component extracted from traditional Chinese medicine, attenuates cisplatin‐induced ototoxicity in vivo and in vitro. The protective effect is achieved by downregulation of Socs1. The present study is the first to investigate the expression and function of Socs1 in inner ear, which is known to promote ferroptosis ...
Yin Chen, Cheng Cheng, Ao Li, Dengbin Ma, Siyu Li, Handong Wang, Song Gao, Dingding Liu, Panpan Song, Chenjie Yu, Xiaoyun Qian, Guoqiang Wan, Xia Gao   +12 more
wiley   +1 more source

α‐Synuclein Pathology Spreads in a Midbrain–Hindbrain Assembloid Model

Advanced Science, EarlyView.
A novel midbrain–hindbrain assembloid model demonstrates the spread of α‐synuclein pathology, a hallmark of Parkinson's disease, mimicking Braak's hypothesis. This model reveals how pathology propagates from the hindbrain to the midbrain, inducing synaptic changes and early signs of neuronal vulnerability. It offers an innovative platform for exploring
Gemma Gomez‐Giro, Daniela Frangenberg, Daniela Vega, Alise Zagare, Kyriaki Barmpa, Paul M. A. Antony, Graham Robertson, Rahman Sabahi‐Kaviani, Kristian Haendler, Nathalie Kruse, Florentia Papastefanaki, Rebecca Matsas, Malte Spielman, Regina Luttge, Jens C. Schwamborn   +14 more
wiley   +1 more source

Deciphering Auditory Hyperexcitability in Otogl Mutant Mice Unravels an Auditory Neuropathy Mechanism

Advanced Science, EarlyView.
By investigating auditory hyperexcitability in a mouse model for hereditary deafness, this study identified a subpopulation of afferent neurons of the auditory nerve marked by Otogl expression. Despite their apparently normal hearing, Otogl+/− mice display poor activation of afferent neurons processing loud sounds and an elevation of the middle the ear
Mathilde Gagliardini, Sabrina Mechaussier, Carolina Campos Pina, Monica Morais, Olivier Postal, Philippe Jean, Typhaine Dupont, Amrit Singh‐Estivalet, Shéhanie Udugampolage, Cyril Scandola, Elisabeth Verpy, Baptiste Libé‐Philippot, Talya C. Inbar, Joanna Schwenkgrub, Carla Maria Barbosa Spinola, Raphaël Etournay, Aziz El‐Amraoui, Brice Bathellier, Adeline Mallet, Sedigheh Delmaghani, Fabrice Giraudet, Christine Petit, Boris Gourévitch, Paul Avan, Nicolas Michalski   +24 more
wiley   +1 more source

Tetrandrine alleviates inflammation and neuron apoptosis in experimental traumatic brain injury by regulating the IRE1α/JNK/CHOP signal pathway

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Aim The aim of this study was to investigate the therapeutic roles of Tetrandrine (TET) on traumatic brain injury (TBI) and the underlying mechanism. Method Traumatic injury model of hippocampal neurons and TBI mouse model were established to evaluate the therapeutic effects.
Huan Liu, Shiqing He, Chong Li, Jianpeng Wang, Qin Zou, Yongshi Liao, Rui Chen   +6 more
wiley   +1 more source