Results 81 to 90 of about 148,622 (241)

Inhibition and Rescue of Hyperglycemia‐Induced Cellular Senescence by Mitochondrial Transfer from Enucleated Mesenchymal Stem Cell‐Derived Microvesicles for Chronic Wound Healing

open access: yesAdvanced Science, EarlyView.
This study develops enucleated MSC‐derived microvesicles (Mito@euMVs) to deliver functional mitochondria for optimizing wound repair. By efficiently encapsulating mitochondria, Mito@euMVs rejuvenate hyperglycemia‐induced senescent fibroblasts and HUVECs. Using PVA microneedle patches, the therapeutic efficacy of Mito@euMVs is validated in diabetic rats
Zixuan Dong   +3 more
wiley   +1 more source

Conducting polymer coated fabrics for potential applications in microwave frequencies : a study of electromagnetic properties

open access: yes, 2007
The microwave reflection, transmission and complex permittivity of paratoluene-2-sulfonic acid doped conducting polypyrrole (PPy/pTSA) coated Nylon-Lycra textiles in the 1-18 GHz frequency were investigated.
Håkansson, Eva, Kaynak, Akif
core  

Delayed Transplantation of Neural Stem Cells Improves Initial Graft Survival after Stroke

open access: yesAdvanced Science, EarlyView.
Delayed transplantation of human iPSC‐derived neural progenitor cells (NPCs) enhances graft survival, proliferation, and axonal sprouting after stroke. Using bioluminescence imaging and histology in a mouse model of stroke, it is shown that NPC delivery at 7 days post‐stroke is more effective than acute transplantation, highlighting the importance of ...
Rebecca Z Weber   +6 more
wiley   +1 more source

A Novel Cranial Bone Transport Technique Repairs Skull Defect and Minimizes Brain Injury Outcome in Traumatic Brain Injury Rats

open access: yesAdvanced Science, EarlyView.
This study introduces a novel, safe, and effective surgical technique: Cranial bone transport (CBT) to improve traumatic brain injury (TBI) outcomes in rats. CBT significantly accelerated skull defect bone repair in addition to its promoting effects on neurological function recovery. This work provides an alternative therapy for patients suffering from
Shanshan Bai   +20 more
wiley   +1 more source

Multifunctional Biomimetic Nanotherapeutics for Anti‐Oxidative and Anti‐Inflammatory Synergistic Therapy of Corneal Neovascularization

open access: yesAggregate, EarlyView.
An anti‐inflammatory and antioxidant metal‐organic framework (MOF) nanoplatform was prepared via one‐pot self‐assembly. In vitro and in vivo studies demonstrated that the prepared MVPC nanoparticles can effectively scavenge overproduced reactive oxygen species at diseased sites, enhance IL‐10 secretion, and suppress VEGFA expression, offering a novel ...
Shundong Cai   +12 more
wiley   +1 more source

Sensor‐Embedded Muscle for Closed‐Loop Controllable Actuation in Proprioceptive Biohybrid Robots

open access: yesAdvanced Intelligent Systems, EarlyView.
Skeletal muscle tissue‐based bioactuators move in response to externally applied electrical stimuli in open‐loop control, which lacks knowledge of the actuator's state. Herein, a soft and fiber‐shaped piezoresistive mechanosensor that integrates with the soft tissue and operates in the cell culture environment is used to create the first proprioceptive
Miriam Filippi   +8 more
wiley   +1 more source

X-ray based virtual histology allows guided sectioning of heavy ion stained murine lungs for histological analysis

open access: yes, 2018
Examination of histological or immunohistochemically stained 2D sections of embedded tissue is one of the most frequently used tools in biomedical research and clinical routine.
Albers, J.   +3 more
core   +1 more source

Early functional and structural hippocampal impairment in a bilateral common carotid artery stenosis mouse model

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Our study used behavioral tests, laser speckle flowmetry, long‐term potentiation, histochemical staining, molecular experiments, and voxel‐based morphometry to evaluate the hippocampal impairments. It demonstrates early functional and structural impairments in the hippocampus contributing to learning and memory deficits after 1 month of BCAS ...
Ping Tang   +3 more
wiley   +1 more source

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