Results 121 to 130 of about 57,043 (220)
Pharmaceutical Statistics, Volume 25, Issue 2, March/April 2026.ABSTRACT Appropriately performing Global Sensitivity Analysis (GSA) and refining models through the estimation of key parameters on individual data are fundamental steps in PBPK modeling, yet they remain insufficiently addressed in current practice. The main aim of this work is to establish a computational framework linking PhysPK with Python, enabling
Marina Cuquerella‐Gilabert +7 more
wiley +1 more source
A Drosophila Model for Clostridium difficile Toxin CDT Reveals Interactions with Multiple Effector Pathways. [PDF]
, 2020 Clostridium difficile infections (CDIs) cause severe and occasionally life-threatening diarrhea. Hyper-virulent strains produce CDT, a toxin that ADP-ribosylates actin monomers and inhibits actin polymerization.
Bier, Ethan +4 more
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PPy‐Coated Wire Actuators for the Micromechanostimulation of Cells: Fabrication and Characterization
Small Science, Volume 6, Issue 3, March 2026.“Ouch!” That's what we say when someone pushes us. Cells do the same. They sense mechanical cues and trigger downstream signals shaping physiological and pathological responses. While the basics of mechanotransduction are known, many pathways remain unexplored.
Amaia B. Ortega‐Santos +5 more
wiley +1 more source
Characterization of Human Pituitary Adenomas in Cell Cultures by Light And Electron Microscopic Morphology And Immunolabeling [PDF]
, 2005 The morphology and hormone production of pituitary adenoma cell cultures were compared in order to highlight their characteristic in vitro features. Cell suspensions were prepared from 494 surgical specimens.
Bácsy, Ernő +6 more
core
Changes in the Mare Oviduct Across Different Seasons Throughout the Year
Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.Checking changes throughout the year in the oviductal structure (anatomy, permeability, oviductal cellularity and the presence of pathologies) may be relevant to understand the influence on the appearance of problems in oviductal functionality. The oviducts of 56 mares were examined, and the correlations between the time of the year and each of these ...
Noelia González +3 more
wiley +1 more source
Investigations into the structure and function of the exocrine pancreas of lampreys. [Translation from: Morph.Jb. 110 245-269, 1967.] [PDF]
, 1967 As representatives of the most primitive of recent vertebrate groups, lampreys show fundamental differences in different features of organisation to the species of the remaining classes of vertebrates.
Ermisch, A., Luppa, H.
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Journal of Physiological InvestigationUterine adenomyosis is an estrogen-dependent chronic inflammatory condition and may cause painful symptoms, abnormal uterine bleeding, and/or subfertility/infertility.
Khaleque N. Khan
doaj +1 more source
Annals of Applied Biology, Volume 188, Issue 2, Page 503-519, March 2026.We investigated the role of vision in host‐seeking behaviour by Philaenus spumarius, the main European vector of Xylella fastidiosa, through an integrated anatomical, optical, physiological, and behavioural study. Our data highlight that the spittlebug uses visual cues, including polarized light, which may aid in detecting the polarized reflections ...
Domen Lazar +4 more
wiley +1 more source
Merlin Phosphorylation by p21-activated Kinase 2 and Effects of Phosphorylation on Merlin Localization [PDF]
, 2002 The Nf2 tumor suppressor gene product merlin is related to the membrane-cytoskeleton linker proteins of the band 4.1 superfamily, including ezrin, radixin, and moesin (ERMs). Merlin is regulated by phosphorylation in a Rac/cdc42-dependent fashion.
Eckman, Matthew S. +3 more
core +1 more source
Soil Organisms, 2010 We studied the process of vitellogenesis in the oribatid mite Archegozetes longisetosus using light and electron microscopy. Both vitellogenesis and the formation of the first egg shell occur within the meroi of the ovary, starting after detachment from
Paavo Bergmann +2 more
doaj