Results 11 to 20 of about 30,901 (212)
Dynamic microvilli sculpt bristles at nanometric scale
Nature CommunicationsOrganisms generate shapes across size scales. Whereas patterning and morphogenesis of macroscopic tissues has been extensively studied, the principles underlying the formation of micrometric and submicrometric structures remain largely enigmatic ...
Kyojiro N. Ikeda +8 more
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Integrated Multi-Omic Analysis Identifies Altered Colonic Brush Border Profile as a Key Feature of Microscopic Colitis. [PDF]
United European Gastroenterol JABSTRACT Background Microscopic colitis (MC), comprising lymphocytic colitis (LC) and collagenous colitis (CC), is an inflammatory bowel disease with increasing incidence. MC etiopathogenesis remains unknown; however, altered colonic epithelial integrity may underlie uncontrolled luminal antigen passage, triggering immuno‐inflammatory responses ...
Guagnozzi D +18 more
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Direct visualization of epithelial microvilli biogenesis [PDF]
Current Biology, 2020 SUMMARYMicrovilli are actin bundle supported surface protrusions that play essential roles in diverse epithelial cell functions. To develop our understanding of microvilli biogenesis, we used live imaging to directly visualize protrusion growth at early stages of epithelial differentiation. Time-lapse data revealed that an “initiation complex” enriched
Isabella Gaeta +4 more
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MICROVILLI OF THE HUMAN JEJUNAL EPITHELIAL CELL [PDF]
The Journal of Cell Biology, 1962 Arnold L. Brown
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NHERF1 in Microvilli of Vomeronasal Sensory Neurons [PDF]
Chemical Senses, 2016 In most mammals, the vomeronasal system detects a variety of (semio)chemicals that mediate olfactory-driven social and sexual behaviors. Vomeronasal chemosensation depends on G protein-coupled receptors (V1R, V2R, and FPR-rs) that operate at remarkably low stimulus concentrations, thus, indicating a highly sensitive and efficient signaling pathway.
Bastian Henkel +4 more
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Surfing on Membrane Waves: Microvilli, Curved Membranes, and Immune Signaling
Frontiers in Immunology, 2020 Microvilli are finger-like membrane protrusions, supported by the actin cytoskeleton, and found on almost all cell types. A growing body of evidence suggests that the dynamic lymphocyte microvilli, with their highly curved membranes, play an important ...
Ron Orbach, Xiaolei Su, Xiaolei Su
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Membrane Ultrastructure and T Cell Activation
Frontiers in Immunology, 2018 The immune system serves as a crucial line of defense from infection and cancer, while also contributing to tissue homeostasis. Communication between immune cells is mediated by small soluble factors called cytokines, and also by direct cellular ...
Johannes Pettmann +4 more
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Retinal Pigment Epithelial Cell Line with Fast Differentiation and Improved Barrier Properties
Pharmaceutics, 2019 Retinal pigment epithelium (RPE) acts as an outer blood−retinal barrier that limits the access of circulating xenobiotics to the eye. In addition, the RPE limits posterior elimination of intravitreally injected drugs to circulation.
Laura Hellinen +4 more
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Isolation of microvilli from mammalian cells [PDF]
FEBS Letters, 1978 Microvilli have a variety of functions in animal cells. On epithelial cells of the renal tubule or small intestine, they increase the absorptive capacity of the cell, by increasing its surface area. In this instance, microvilli are concentrated at one end of the cells, in the form of ‘brush border’, and may be isolated as such and their composition ...
Kaur, Baldip +2 more
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Memorias do Instituto Oswaldo Cruz, 2004 The effects of blood components, nerve-cord severance, and ecdysone therapy on the posterior midgut epithelial cells of 5th-instar Rhodnius prolixus nymphs 10 days after feeding were analyzed by transmission electron microscopy. Cutting the nerve-cord of
JM Albuquerque-Cunha +6 more
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